男≤55岁，女≤65岁左冠状动脉夹角与冠状动脉硬化的相关性研究  

The study of relationship of coronary atherosclerosis with the bifurcation angle of left coronary artery in males ≤55 years of age and females ≤65 years of age

作　　者：刘晓蓓 潘存雪 刘文亚 LIU Xiaobei;PAN Cunxue;LIU Wenya(Imaging Center,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China)

机构地区：[1]新疆医科大学第一附属医院影像中心,新疆乌鲁木齐830054

出　　处：《实用放射学杂志》2018年第9期1359-1362,共4页Journal of Practical Radiology

基　　金：乌鲁木齐市科学技术计划项目（Y121320019）。

摘　　要：目的 利用MSCT分析新疆地区男≤55岁，女≤65岁受检者左冠状动脉分叉夹角与夹角近段管壁动脉粥样硬化的相关性。方法 纳入新疆地区，临床疑为早发冠心病并行冠状动脉CT血管成像（CTA）检查的患者685例（男366例，女319例），回顾性分析评估受检者冠状动脉粥样硬化斑块发生部位及狭窄程度，参照Djaberi的分级标准，将左冠状动脉夹角近段管腔分为Ⅰ～Ⅳ级,分析受检者左冠状动脉夹角与左冠状动脉夹角近段管壁粥样硬化之间的关系。结果 冠状动脉脉粥样硬化斑块主要累及邻近左冠状动脉分叉夹角的管壁，男为95.17%（197/207），女为95.28%（121/127）；男366例受检者中，Ⅰ～Ⅳ分级者数及百分比各为176（48.10%），151（41.30%），24（6.60%），15（4.10%），相应夹角均值分别为（92±32.8）°，（101±35）°，（100±51）°，（96±39）°，男性Ⅰ级左冠状动脉夹角明显小于Ⅱ级（P=0），但男Ⅰ与Ⅲ、Ⅳ级及Ⅲ、Ⅳ级之间差异无统计学意义。女319例受检者中，Ⅰ～Ⅳ分级者数及百分比各为204（63.90%），70（21.90%），34（10.70%），11（3.40%），相应夹角均值分别为（71±29）°，（85±28）°，（87±17）°，（85±15）°，女Ⅰ级的左冠状动脉夹角明显小于Ⅱ、Ⅲ、Ⅳ级（P=0），Ⅱ、Ⅲ、Ⅳ级之间差异无统计学意义。结论 男≤55 岁，女≤65 岁冠状动脉脉粥样硬化斑块主要累及临近左冠状动脉分叉夹角的管壁，大的左冠状动脉夹角可能导致夹角区管壁粥样硬化，但与病变发生的程度无明显相关性。Objective To explore the relationship between left coronary artery bifurcation angle and coronary atherosclerosis in males ≤55 years of age and females ≤65 years of age in Xinjiang by MSCT.Methods 685 individuals （366 males,319 females） with clinically suspected early-onset coronary artery disease who all had taken coronary CTA examinations in Xinjiang were enrolled, and the images were retrospectively analyzed of plaques location and level of stenosis.According to Djaberi＇ classification,the stenosis of proximal lumen adjacent to left coronary artery bifurcation angle region was classified as Ⅰ- IV .The relationship were analyzed between the angle of left coronary artery bifurcation and atherosclerosis in corresponding region. Results Coronary atherosclerotic plaques mainly involved the arterial walls near left coronary artery bifurcation angle region, with male 95.17 %（197/207） and female 95.28 （ 121/127 ）. Among 366 male subjects, the numbers of Grade Ⅰ- Ⅳ and corresponding percentages were 176 （ 48.10%）, 151 （ 41.30%）, 24（6.60%） and 15（4.10%）, respectively.The average of corresponding grades were （92±32.8）°, （101±35）°, （100±51）°and （96±39）°, respectively.The male left coronary artery bifurcation angle in Grade Ⅰ was significantly smaller than that in Grade Ⅱ（P = 0）, whereas no significant differences left coronary artery bifurcation angle between Grade Ⅰ ,Ⅲ and Ⅳ, Grade Ⅲ and Ⅳ had no significant difference also. Among 319 female subjects, 204 （ 63.90%）, 70 （ 21.90 % ）, 34 （ 10.70% ） and 11 （ 3.40%） were respectively classified as Grade Ⅰ - Ⅳ, whose average left coronary artery bifurcation angle were （ 71 ± 29 ）°, （ 85 ±28 ）°, （ 87 ± 17 ）° and （ 85 ±15 ）° respectively. The female left coronary artery bifurcation angle in Grade Ⅰ was significantly smaller than those in Grade Ⅱ, Ⅲ and Ⅳ（P = 0 ）. However, there were no statistically differences among Ⅱ, Ⅲ , Ⅳ.Conclusion

关 键 词：左冠状动脉分叉夹角 冠状动脉粥样斑块 计算机体层成像 

分 类 号：R322.1[医药卫生—人体解剖和组织胚胎学] R543.3[医药卫生—基础医学]