胃癌组织横向剪切波速度与患者临床特征的关系  

The relationship between the shear wave velocities of gastric cancer tissues and clinical characteristics of gastric cancer patients

作　　者：王小花[1] 何慧疗[1] 姜淑英[1] 林益怡[1] WANG Xiaohua;HE Huiliao;JIANG Shuying;LIN Yiyi(Department of Ultrasound,the Second Affiliated Hospital of Wenzhou Medical University,Wenzhou,32502)

机构地区：[1]温州医科大学附属第二医院超声影像科,浙江温州325027

出　　处：《温州医科大学学报》2018年第9期688-690,693,共4页Journal of Wenzhou Medical University

摘　　要：目的:探讨胃癌组织横向剪切波速度与胃癌患者临床特征之间的关系。方法:应用基于超声的声辐射力脉冲成像技术中声触诊组织定量技术对53例胃癌患者胃壁病灶进行超声弹性量化检测,分析胃癌组织横向剪切波速度在不同性别、年龄、肿瘤大小、部位、浸润深度、淋巴结转移及组织学分化程度等临床特征间的差异。结果:胃癌组织横向剪切波速度在不同年龄、性别、分化程度、肿瘤大小及发生部位间差异无统计学意义(P>0.05);在浸润深度及有无淋巴结转移方面差异均有统计学意义(P<0.05),胃癌组织的横向剪切波速度随浸润深度加深而增加,有淋巴结转移者高于无淋巴结转移者。多因素回归分析显示,淋巴结转移与胃癌组织横向剪切波速度呈正相关。结论:胃癌组织横向剪切波速度与有无淋巴结转移有关,可作为评价胃癌患者有无淋巴结转移以及肿瘤浸润深度的一项辅助指标。Objective： To investigate the relationship between the shear wave velocities of gastric cancer tissues and clinical characteristics in gastric cancer patients. Methods： A total of 53 patients with gastric cancer confirmed by operative pathology underwent an ultrasound-based acoustic radiation force impulse （ARFI） technique before the surgery. The shear wave velocity was obtained using virtual tough tissues quantification （VTQ） of ARFI technique, and the relationship between the findings of VTQ in gastric cancer tissues and clinical characteristics in gastric cancer patients were analyzed, including their sex and age, size of lesions, the tumor location, invasive depth, lymph node metastases, and degree of tissue differentiation. Results： The preoperative shear wave velocities of gastric cancer tissues were not correlated with sex and age of the patients or size and location of the tumor （P〉0.05）. There was no significant difference in the degree of tissue differentiation （P〉0.05）. The shear wave velocities of gastric cancer tissues in patients with lymph node metastases were higher than those in patients without lymph node metastases （P〈0.05）, and they were positively correlated with the depth of tumor invasion （P〈0.05）. Multiple linear regression analysis revealed lymph node metastases were related with the shear wave velocities of gastric cancer tissues. Conclusion： The shear wave velocities of gastric cancer tissues were positively related with lymph node metastases. It may be considered a helpful index in assessing gastric cancer and provide basis for the formulation of the therapeutic regimen of the gastric cancer patients.

关 键 词：超声检查 弹性成像技术 胃肿瘤 病理 

分 类 号：R445.1[医药卫生—影像医学与核医学]