经尿道前列腺等离子双极电切术对BPH患者术后性功能及血清PSA、PGI2水平变化的影响  

Effects of transurethral plasma kineticvaporization prostatectomy on postoperative sexual function and serum PSA and PGI2 levels in patients with BPH

作　　者：唐亚雄[1] 吕天兵[1] 傅承忠[1] 邓颖[2] 陈雪芹[3] TANG Yaxiong;LV Tianbing;FU Chengzhong;DENG Ying;CHEN Xueqin(Department of Urology,Neijiang First People＇s Hospital,Neijiang 641000,Siehuan,China;Oneology Center,Sichuan Pravineial People＇s Hospital,Chengdu 610072,Sichuan,China;Pathology laboratory,The West China Hospital of Sichuan University,Chengdu 610041,Siehuan,China)

机构地区：[1]内江市第一人民医院泌尿外科,四川内江641000 [2]四川省人民医院肿瘤中心,成都610072 [3]四川大学华西医院病理研究室,成都610041

出　　处：《中国性科学》2018年第8期21-25,共5页Chinese Journal of Human Sexuality

基　　金：国家自然科学基金(81101939)

摘　　要：目的:探讨经尿道前列腺等离子双极电切术对良性前列腺增生(BPH)患者术后性功能及血清前列腺特异性抗原(PSA)、前列环素(PGI2)水平变化的影响。方法:选取内江市第一人民医院89例BPH患者,依据手术术式不同分组,对照组44例给予气化电切术治疗,观察组45例给予经尿道前列腺等离子双极电切术治疗,观察比较两组手术情况[尿管留置时间、术中出血量、术后视觉模拟评分(VAS)]及手术前后国际前列腺症状(IPSS)评分、性功能各指标[国际勃起功能指数(IIEF-5)评分、早泄患者性功能-5(CIPE-5)评分]及血清PSA、PGI2水平变化情况,并统计两组并发症发生情况。结果:与对照组相比,观察组尿管留置时间短、术中出血量少、术后VAS评分及术后IPSS评分均较对照组低,差异具有统计学意义(P <0. 05);观察组术后IIEF-5及CIPE-5评分均高于对照组,差异具有统计学意义(P <0. 05);观察组术后血清PSA水平低于对照组,血清PGI2水平高于对照组,差异具有统计学意义(P <0. 05);观察组并发症发生率为4. 44%(2/45),低于对照组20. 45%(9/44),差异具有统计学意义(P <0. 05)。结论:采用经尿道前列腺等离子双极电切术治疗可改善BPH患者术后性功能及血清PSA、PGI2水平,效果显著,并发症发生率低。Objective：To investigate the effect of transurethral plasma kinetievaporization prostateetomy on postoperative sexual function and serum prostate specific antigen （PSA） and prostaeyelin （PGI2） levels in patients with benign prostatic hyperplasia （BPH）. Methods ：89 patients with BPH in Neijiang First People＇s Hospital were selected and divided into control group （n = 44） and observation group （n = 45 ） according to different surgical procedures. The control group was given eleetrovaporization, while the observation group was given transurethral plasma kinetievaporization prostateetomy. Surgery- condition I catheter retention time, intraoperative blood loss, postoperative visual analogue scale （VAS） 1, the International Prostate Symptom （IPSS） score before and after surgery, the indicators of sexual function I International index of erectile function （IIEF-5） score, China index of the sexual function of premature ejaculation patients （CIPE-5） seorel and changes in serum PSA, PGI2 levels were observed and compared between the two groups, and the incidence of complications was statistically analyzed. Results： The intraoperative blood loss, catheter retention time and postoperative VAS score in the observation group were lower than those in the control group, with statistically significant difference （P 〈 0. 05）. The IPSS score of the observation group was lower than that of the control group after treatment, with statistically significant difference （ P 〈 0. 05）. After treatment, the scores of IIEF-5 and CIPE-5 of the observation group were significantly higher than those of the control group, with statistically significant difference （ P 〈 0. 05 ）. The serum PSA level in the observation group was significantly lower than that in the control group, and the level of serum PGI2 was significantly higher than that of the control group, all with statistically significant differences （ P 〈 0. 05 ）. The incidence of complications in the observation group �

关 键 词：良性前列腺增生 经尿道前列腺等离子双极电切术 性功能 血清前列腺特异性抗原 前列环素 

分 类 号：R699.8[医药卫生—泌尿科学]