妊娠期阴道假丝酵母菌感染与胎膜早破的关系及对母婴结局的影响  

Relationship of vulvovaginal candidiasis infection in gestation period and premature rupture of membranes andits influence on maternal and neonatal outcomes

作　　者：张燕[1] 林曼[1] 王秀妹[1] ZHANG Yan;LIN Man;WANG Xiumei(Department of Obstetrics and Gynecology,Haikou Maternal and Child Heahh Care Hospital,Haikou 570102,Hainan,China)

机构地区：[1]海口市妇幼保健院妇产科,海口570102

出　　处：《中国性科学》2018年第8期77-79,共3页Chinese Journal of Human Sexuality

摘　　要：目的:探讨妊娠期阴道假丝酵母菌感染与胎膜早破的关系及对母婴结局的影响。方法:选择2015年2月至2016年10月海口市妇幼保健院收治的104例妊娠期假丝酵母菌感染孕妇作为观察组,另选择同期来我院定期产检的130例正常妊娠孕妇作为对照组。比较两组研究对象胎膜早破发生率以及早产、产褥感染、绒毛膜羊膜炎等母婴结局。结果:观察组孕妇胎膜早破发生率为30. 7%,对照组孕妇胎膜早破发生率为9. 2%,两组比较有明显统计学差异(χ~2=17. 56,P <0. 01)。假丝酵母菌感染患者早产、产褥感染、绒毛膜羊膜炎、新生儿肺炎、围产儿死亡以及新生儿窒息发生率高于对照组,差异具有统计学意义(P <0. 05)。而两组在产后出血、胎儿窘迫、新生儿窒息以及新生儿病理性黄疸的发生率差异无统计学意义(P>0. 05)。结论:假丝酵母菌感染会不仅增加妊娠期孕妇胎膜早破的风险,还会影响其他不良母婴结局的发生。Objective：To explore the relationship of vulvovaginal candidiasis infection in gestation period and premature rupture of menlbranes and its influenee on maternal and neonatal outcomes. Methods： 104 pregnant women with eandida infection in gestation period treated in Haikou Maternal and Child Health Care Hospital from February 2015 to October 2016 were selected as the observation group, and 130 normal pregnant women for normal antenatal care in the same period in the hospital were selected as the control group. The incidence of premature rupure of mentbranes, premature, puerperal infeetion, ehorioanmionitis and other maternal and neonatal outcomes were compared between the two groups. Results： The incidence of premature rupture of membranes in the observation group and control group was 30.7% and 9. 2% respectively, with statistically significant difference between the two groups （x2 = 17. 56, P 〈 0. 01 ）. The incidence rate of premature delivery, puerperal infeetion, ehorioamnionitis, neonatal pneumonia, perinatal death, and neonatal asphyxia was higher than that of the control group, with statistically significant difference （ P 〈 0. 05 ）. There was no significant difference in the incidence of postpartum hemorrhage, fetal distress, neonatal asphyxia and neonatal pathologic jaundice between the two groups （P 〉 0. 05）. Conclusions ： Candida infection can increase the risk of premature rupture of membranes in pregnant women, which also affects the occurrence of other adverse maternal and fetal outcomes.

关 键 词：假丝酵母菌病 胎膜早破 母婴结局 真菌感染 

分 类 号：R714.433[医药卫生—妇产科学]