自发性早产的免疫学研究进展  

Research Progress of Spontaneous Preterm Labor in Immunology

作　　者：蒋敏[1] 姚延娇 谢艳艳 卢丹[1] JIANG Min;YAO Yanjiao;XIE Yanyan;LU Dan(Department of Gynecology and Obstetrics,Clinical Medical College,Yangzhou University,Northern Jiangsu People＇s Hospi tal,Yangzhou 225001,China)

机构地区：[1]扬州大学临床医学院江苏省苏北人民医院妇产科,江苏扬州225001

出　　处：《医学综述》2018年第18期3548-3553,共6页Medical Recapitulate

基　　金：江苏省妇幼健康科研项目(F201663);扬州市科技计划项目(YZ2017075)

摘　　要：早产是围生儿发病率和病死率升高的最主要因素,但其病因和发病机制尚不十分清楚,尤其是自发性早产。近年来,随着研究者对自发性早产发病机制及预测措施的重视,其病因学研究已取得较大进展,其中妊娠相关免疫学研究已逐渐认识到免疫机制在自发性早产发病中的重要作用。而非特异性免疫、特异性免疫及遗传因素均与自发性早产的发生、发展密切相关,这为自发性早产免疫学发病机制的深入研究及免疫预测方法、免疫干预措施的研发提供了新方向。Preterm labor is the major factor for the incidence and mortality increase of perinatal infants,but its etiology and pathogenesis are not clear, especially the spontaneous preterm labor. In recent years, as researchers have paid more attention to the pathogenesis and forecasting measures of spontaneous preterm labor,its etiological study has made great pro-gress. Especially research on pregnancy related imnmnology has gradually realized that the inmmnologie meehanisnl play-s an important role in the onset of spontaneous preterm labor. Non-specific imnmnity, specific imnmnity and genetic factors are closely related to the occurrence and development of spontaneous preterm labor,which provides new ideas for the further study of inmmnologieal mechanism,and development of immunological prediction and intervention methods.

关 键 词：自发性早产 非特异性免疫 特异性免疫 遗传因素 

分 类 号：R714.21[医药卫生—妇产科学]