固肾益气排石协定方对经皮肾镜碎石术后残留结石的治疗效果  

Therapeutic effect of Gushen Yiqi Paishi Formula on Patients with Residual Stones after Percutaneous Nephrolithotomy

作　　者：霍振清[1] 罗后宙 梁冰 朱家利 汪溢[1] 姚泽钦 HUO Zhenqing;LUO Houzhou;LIANG Bing;ZHU Jiali;WANG Yi;YAO Zeqin(Department of Urology,Third People＇s Hospital of Hainan,Sanya 572000,Hainan,China)

机构地区：[1]海南省第三人民医院泌尿外科

出　　处：《中华中医药学刊》2018年第9期2277-2280,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：海南省卫生厅科研项目(琼卫2014-30)

摘　　要：目的：评价固肾益气排石协定方对经皮肾镜碎石术后残留结石患者的治疗效果。方法：上尿路结石患者126例,根据Excel随机数字表格法,将患者分为研究组和对照组,每组63例。对照组采取经皮肾镜碎石术治疗,术后给予常规药物治疗,研究组在对照组治疗的基础上给予固肾益气排石协定方治疗,共治疗8周。比较两组治疗前后中医症候积分、治疗疗效、平均结石排净时间、疼痛消失时间、住院时间和1年内复发率。结果：研究结果显示,两组治疗前中医症候积分比较差异无统计学意义（P〉0.05）;两组患者治疗后中医症候积分显著低于治疗前（P〈0.05）;研究组治疗后中医症候积分显著低于对照组（P〈0.05）;研究组治疗前后中医症候积分差值显著大于对照组（P〈0.05）;研究组治疗总有效率为90.48%显著高于对照组治疗总有效率的76.19%（P〈0.05）;研究组结石排净时间、疼痛消失时间和住院时间显著低于对照组（P〈0.05）;两组患者均获得1年以上随访,两组患者在随访3个月时复发率比较差异无统计学意义（P〉0.05）,研究组在随访半年及随访1年时复发率显著低于对照组（P〈0.05）。结论：固肾益气排石协定方可以有效的促进经皮肾镜碎石术后残留结石的排出,显著改善上尿路结石患者的临床症状,提高治疗疗效,降低术后1年复发率,值得临床推广应用。Objective： To evaluate the curative effect of Gushen Yiqi Paishi Formula on the patients with residual stone after percutaneous nephrolithotomy. Methods： 126 patients with upper urinary calculi were randomly divided into the study group and the control group according to the Excel random number table method,63 cases in each group. The control group was treated by percutaneous nephrolithotomy,and the routine medication was given after treatment. The study group was given Gushen Yiqi Paishi Formula on the basis of the control group＇s treatment for 8 weeks. The TCM syndrome score,the therapeutic effect,the average stone discharge time,the time of pain disappearance,the time of hospitalization and the rate of recurrence within 1 year were compared between the two groups. Results： The results showed that the comparison of TCM syndrome score had no significant difference between the two groups before treatment（ P 〉0. 05）.Two groups＇ TCM syndrome score after treatment was significantly lower than that before treatment（ P 〈0. 05）. TCM syndrome score of the study group after treatment was significantly lower than that of the control group（ P 〈0. 05）. The study group＇s traditional Chinese medicine syndrome integral before and after treatment was significantly greater than that of the control group（ P 〈0. 05）. The treatment group＇s total effective rate was 90. 48%,which was significantly higher than the control group＇s 76. 19%（ P 〈0. 05）. The study group＇s lithagogue time,the pain disappeared time and hospitalization time were significantly lower than those of the control group（ P〈 0. 05）. Two groups were followed up for more than 1 year. During the follow-up there was no significant difference in the recurrence rate at 3 months（ P 〉0. 05）. In the study group,the recurrence rates of six months and 1 yearfollow-up were significantly lower than those of the control group（ P 〈0. 05）. Conclusion： Gushen Yiqi Paishi Formula can effectively promote the excretion

关 键 词：上尿路结石 经皮肾镜碎石术 残留结石 疗效 

分 类 号：R692.4[医药卫生—泌尿科学]