中药益气健脾和胃法治疗乳腺癌患者术后化疗胃肠反应的效果  

Effect of Chinese herbal medicine Yiqi Jianpi Hewei Therapy on postoperative gastrointestinal reaction of patients with breast cancer after chemotherapy

作　　者：陈绮云[1] 傅晓芸[1] 陈凤兰[1] 

机构地区：[1]东莞市人民医院,广东东莞523000

出　　处：《中医临床研究》2018年第24期98-100,共3页Clinical Journal Of Chinese Medicine

摘　　要：目的:探析中药益气健脾和胃法治疗乳腺癌患者术后化疗胃肠反应的效果。方法:选取我院于2016年1月—2017年12月收治的56例乳腺癌患者为主要研究对象,所有患者均接受乳腺癌改良根治术的术后化疗。采用数字随机表达法将其分为两组,对照组和观察组各28例。对照组患者给予西药方案调理,观察组患者给予中药益气健脾和胃法治疗,对两组患者的胃肠道不良反应(恶心呕吐、食欲下降、腹泻、便秘)发生情况、生存质量和术后复发情况进行对比分析。结果:(1)经治疗后,观察组患者在恶心呕吐、食欲下降、腹泻、便秘等胃肠不良反应方面的发生率明显低于对照组,两组数据对比差异有统计学意义(P<0.05);(2)两组患者治疗前的生存质量评分对比差异无统计学意义(P>0.05),观察组患者的各项生存质量评分明显高于对照组,两组差异有统计学意义(P<0.05);(3)观察组的术后复发率为17.86%,对照组患者的术后复发率为46.49%,经统计学分析,观察组的复发率明显低于对照组,两组对比差异显著,有统计学意义(P<0.05)。结论:中药益气健脾和胃法治疗乳腺癌患者术后化疗胃肠反应的效果显著,同时可降低患者术后病灶的复发率,提高机体免疫力,从而提升患者的生存质量。中药调理方案兼具安全性和有效性,故值得在临床上进一步推广和应用。Objective： To explore the effect of Effect of Chinese herbal medicine Yiqi Jianpi Hewei Therapy （益气健脾和胃法） on postoperative gastrointestinal reaction of patients with breast cancer after chemotherapy. Methods：56 breast cancer patients who were treated in our hospital from January 2016 to December 2017 were selected as the main study subjects. All patients received postoperative chemotherapy for modified radical mastectomy. They were divided into two groups by using the digital random method, with 28 cases in the control group and 28 cases in the observation group. Patients in the control group were given Western medicine regimen conditioning, and patients in the observation group were given Chinese herbal medicine Chinese herbal medicine Yiqi Jianpi Hewei Therapy （益气健脾和胃法） to treat gastrointestinal adverse reactions （nausea and vomiting, loss of appetite, diarrhea, constipation）. The quality of life, and surgery for both groups of patients and the recurrence was given a comparative analysis. Results：1.After treatment, the incidence of nausea and vomiting, loss of appetite, diarrhea, constipation and other gastrointestinal adverse reactions were significantly lower in the observation group than that in the control group. There was a statistically significant difference between the two groups （P〈0.05）. 2.There was no significant difference in quality of life scores before treatment between the two groups （P〉0.05）. After treatment, the quality of life scores in the observation group were significantly higher than those in the control group. There was a statistically significant difference between the two groups （P〈0.05）; 3.The postoperative recurrence rate was 17.86% in the observation group and 46.49% in the control group. After statistical analysis, the recurrence rate in the observation group was significantly lower than that in the control group. There was a statistically significant difference between the two groups （P〈0.05）. Conclusion�

关 键 词：中药 益气健脾和胃法 乳腺癌患者 化疗 胃肠反应 

分 类 号：R273[医药卫生—中西医结合]