丝素蛋白纳米纤维静电纺制备的研究  

Research Progress of the Electrospinning Preparation of Silk Fibroin Nanofibers

作　　者：唐培朵[1] 戴俊[2] 韦凌志 黄华林[1] Tang Pei-duo;Dai Jun;Wei Ling-zhi;Huang Hua-lin(l.Guangxi Academy of Sciences,Guangxi Nanning 53000;Institute of Applied Physics,Guangxi Academy of Sciences,Guangxi Nanning 530003)

机构地区：[1]广西科学院,广西南宁530003 [2]广西科学院应用物理研究所,广西南宁530003

出　　处：《生物化工》2018年第4期118-120,128,共4页Biological Chemical Engineering

基　　金：广西科学院基本科研业务费资助项目(2017YJJ23007)

摘　　要：静电纺丝技术是制备超细纤维和纳米纤维的一种常用方法,以天然或者合成聚合物为原料,可以制备出直径范围为几十纳米至几微米的纤维。利用静电纺丝制备的丝素蛋白(SF)纳米纤维材料,不仅能有效地保持SF原有的优良特性,而且还具有三维多孔结构,比表面积大及孔隙率高等特征,并能高度模仿细胞外基质结构,促进组织再生,可广泛应用于组织工程、医药工程等许多领域。本文主要综述了近年来国内外静电纺丝制备SF纳米纤维材料,特别是在溶剂选择方面的研究现状,并对SF纳米纤维发展进行了展望。Electrospinning is a common preparation method of the superfine fiber and nanometer fiber, with natural or synthetic polymer as raw material, can be prepared the diameter of fibers from nanometers to several microns. The silk fibroin（SF） nanofibers with electrospinning, not only keep the good features of SF, but also have a threedimensional porous structure, and have the higher surface area and porosity, can imitate the structure of extracellular matrix, and highly promote tissue regeneration, which can be widely applied in many fields such as tissue engineering, pharmaceutical engineering. At home and abroad the research status of the preparation of silk fibroin nanofibers materials with electrospinning in recent years was reviewed in this paper, especially solvent selection, and prospected its development of the SF nanofibers in the future.

关 键 词：静电纺丝 丝素蛋白 纺丝溶剂 仿生制备 

分 类 号：TQ340.64[化学工程—化纤工业]