早期应用大剂量静脉丙种球蛋白治疗新生儿溶血病的临床研究  

Clinical study of early application of high dose intravenous immunoglobulin in the treatment of neonatal hemolytic disease

作　　者：刘德坚 Liu Defian(The People＇s Hospital of Taojiang CounLv,Hunan 413400)

机构地区：[1]桃江县人民医院,湖南413400

出　　处：《中国社区医师》2018年第28期34-35,共2页Chinese Community Doctors

摘　　要：目的:探讨新生儿溶血病早期应用大剂量静脉丙种球蛋白进行治疗的方法及效果。方法:收治新生儿溶血病患者100例,分为对照组和研究组,每组各50例。对照组在产生病理性黄疸之后应用大剂量静脉丙种球蛋白治疗,研究组在确诊时接受大剂量静脉丙种球蛋白治疗,比较两组治疗效果。结果:治疗后,研究组血红蛋白值明显高于对照组,黄疸消退时间显著短于对照组(P<0.05)。结论:对新生儿溶血病患者开展大剂量静脉丙种球蛋白早期治疗效果理想,患者黄疸消退时间比较快。Objective：To explore the method and effect of early application of high dose intravenous immunoglobulin in the treatment of neonatal hemolytic disease.Methods：100 patients with neonatal hemolytic disease were selected,they were divided into the control group and the study group.The control group was treated with large doses intravenous immunoglobulin after the production of pathological jaundice,the study group was treated with large doses intravenous immunoglobulin at the time of diagnosis,we compared the treatment effect of two groups.Results：After treatment,the hemoglobin value of the study group was significantly higher than that of the control group,and jaundice subsided time was significantly lower than that of the control group（P 〈 0.05）.Conclusion：The effect of early application of high dose intravenous immunoglobulin in the treatment of neonatal hemolytic disease was ideal,the patient＇s jaundice subsided time was relatively- fast.

关 键 词：新生儿溶血病 大剂量静脉丙种球蛋白 治疗效果 

分 类 号：R722.18[医药卫生—儿科]