无皮肤表现的母细胞性浆细胞样树突状细胞肿瘤报告及护理体会  

The report and nursing experience for BPDCN with no skin manifestation

作　　者：王倩倩[1] 王蕾[1] 

机构地区：[1]山东省枣庄市立医院,山东枣庄277102

出　　处：《中医临床研究》2018年第25期126-128,共3页Clinical Journal Of Chinese Medicine

摘　　要：母细胞性浆细胞样树突状细胞肿瘤(BPDCN),是一种罕见的血液系统侵袭性恶性肿瘤,常见伴发皮肤病变及迅速进展为骨髓受累。老年患者多见。目前大多数报道的BPDCN病例有皮损,没有皮肤病变的病例仅占3%。本研究报道了一例62岁男性在明显血小板减少的情况下,白细胞增多、贫血,但无皮肤病变。骨髓涂片检查发现大量细胞异常增生。骨髓病理免疫组化染色CD4、CD56和CD123均为阳性。患者采用CHOP方案(环磷酰胺+多柔比星+长春新碱+甲基泼尼松龙)化疗,护理要点包括:常规护理(休息、饮食指导)、病情观察、心理护理、健康指导等。在成分输血,CHOP方案化疗的前提下,加强病情观察和个性化的护理措施及健康指导对母细胞性浆细胞样树突状细胞肿瘤患者的治疗及康复起着重要的作用。Blastic plasmacytoid dendritic cell neoplasm （BPDCN） is a rare invasive malignancy in blood system, and is commonly associates with skin lesions and develops to bone marrow involvement. BPDCN typically occurs in the elderly. Most cases of BPDCN have been reported with skin lesions, only 3% cases of BPDCN were diagnosed without skin presentation. A 62-year-old male who sufered from evident thrombocytopenia, leukocytosis and anemia, without skin lesions was reported at present. A large number of abnormally proliferating cells were detected by bone marrow smear. Immunohistochemical staining of BM biopsy shows positive in CD4, CD56, and CD123. The patient was treated by chemotherapy with CHOP and given routine care （rest, diet instruction）, condition observation, psychological care and health guidance. On the basis of component transfusion and chemotherapy with CHOP, enhancing observation and personalized care play an important role in the treatment and rehabilitation.

关 键 词：母细胞性浆细胞样树突状细胞肿瘤 无皮肤病变 护理 

分 类 号：R273[医药卫生—中西医结合]