102例突发性聋患者近期与远期疗效及预后的影响因素比较  

Comparison of the short-term and long-term curative effect and prognosis of 102 patients with sudden deafness

作　　者：朱晓月 王巍[2] 陈鱼[2] 王悦[2] 陈晨[2] 林鹏[2] ZHUXiaoyue;WANG Wei;CHEN Yu;WANG Yue;CHENChen;LIN Peng(The First Center Clinical College,Tianjin Medical University,Tianjin,300192,Chinas;Tianjin Institute of Otolaryngology,Department of Otolaryngology Head and Neck Surgery,the First Central Hospital of Tianjin)

机构地区：[1]天津医科大学一中心临床学院,天津300192 [2]天津市第一中心医院耳鼻咽喉头颈外科天津市耳鼻喉科研究所

出　　处：《临床耳鼻咽喉头颈外科杂志》2018年第17期1325-1331,共7页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

基　　金：天津市应用基础与前沿技术研究计划(No:15JCYBJC27500)

摘　　要：目的:比较102例突发性聋(突聋)患者近期与远期疗效及预后的影响因素。方法:回顾性分析2012-2014年就诊的102例突聋患者的临床资料,对患者在治疗2周后和出院后3～5年分别复测纯音听阈,比较近期与远期疗效及预后的影响因素。结果:102例突聋患者近期总有效率为56.86%,远期总有效率为69.61%,在影响因素相同的情况下,远期总有效率大于近期总有效率,差异有统计学意义(均P<0.05)。进一步分析突聋的预后影响因素发现,听力曲线类型、血流变、血脂(TC、LDL、HDL)、年龄为突聋近期与远期相同的预后影响因素,不同听力曲线类型、血流变正常组与异常组、血脂正常组与异常组,不同年龄段组,各组间疗效结果比较差异有统计学意义(均P<0.05)。而近期与远期的预后影响因素是有区别的,近期疗效与血糖、TG有关,其中血糖正常组与异常组、TG正常组与异常组之间疗效比较差异有统计学意义(均P<0.05)。结论:突聋的远期疗效优于近期疗效。Objective：To compare the short-term and long-term curative effect and prognostic factors of 102 patients with sudden deafness.Method：The clinical data of 102 patients with sudden deafness from 2012 to 2014 were analyzed retrospectively.Pure tone hearing thresholds were measured in patients with sudden deafness for 2 weeks after treatment and 3 to 5 years after discharge,in order to evaluate the short-term and long-term effects,and related prognostic factors were also compared.Result：The short-term total effective rate of 102 patients with sudden deafness was 56.86%,and the long-term total effective rate was 69.61%.Under the same influence factors（female group,TG abnormal group,LDL abnormal group,HDL abnormality,blood rheology abnormality）,the long-term total effective rate was greater than the short-term total effective rate（P〈0.05）,the difference was statistically significant.Further analysis of the influencing factors of the prognosis of sudden deafness found that audiogram shapes,blood rheology and blood lipid（TC,LDL,HDL）,age,were the same prognostic factors of sudden deafness.Different audiogram shapes,normal and abnormal hemorheology group,normal blood lipid group and abnormal group,the curative effect of different age groups,the difference which the results of each group were compared was significant（P〈0.05）.However,there were differences between short-term and longterm prognostic factors.The short-term prognostic factors were also related to blood glucose and TG,The difference between normal blood glucose group and abnormal was significant（P〈0.05）.The difference between the normal TG group and the abnormal group was compared,the difference was significant（P〈0.05）.Conclusion：The long-term curative effect of sudden deafness was better than that of the short-term.

关 键 词：聋 突发性 预后 因素分析 

分 类 号：R764.43[医药卫生—耳鼻咽喉科]