组织工程用局部释氧材料的研究进展  

Research Progress of Topical Oxygen-Releasing Materials for Tissue Engineering

作　　者：裴大婷[1] 刘群峰[1] 耿志杰[1] 张锦[1] 张泽荣[1] PEI Dating;LIU Qunfeng;GENG Zhijie;ZHANG fin;ZHANG Zerong(National Engineering Research Center for Healthcare Devices,Guangdong Key Lab of Medical Electronic Instruments and Polymer Material Products,Guangdong Institute of Medical Instruments,Guangzhou 510500,China)

机构地区：[1]国家医疗保健器具工程技术研究中心广东省医用电子仪器及高分子材料制品重点实验室广东省医疗器械研究所,广东广州510500

出　　处：《临床医学工程》2018年第9期1270-1272,共3页Clinical Medicine & Engineering

基　　金：广东省科技计划项目(项目编号:2017A070702010);广州市科技计划项目(项目编号:201704030067)

摘　　要：释氧材料是一类以高分子聚合物为基底,负载携氧基体或生氧化合物,能够向伤口组织部位持续提供氧气,满足细胞受损修复和新陈代谢需要,促进组织修复和创伤愈合,具有良好生物相容性的材料,适用于局部氧疗,在组织再生工程中具有广泛的应用前景。目前比较热门的释氧材料包含全氟化碳类、无机过氧化物盐类及过氧化氢三类。本文主要概述了这三类释氧材料的国内外研究进展。Oxygen-releasing materials are a class of polymers that are based on high molecular polymers, loaded oxygen carriers or oxygen-producing compounds. They can continually provide oxygen to wound tissues, promote tissue repair and wound healing to meet the needs of cellular damage repair and metabolism, with good biocompatibility. They are suitable for topical oxygen therapy and have wide application prospects in tissue regeneration engineering. At present, perfluorocarbons, inorganic peroxide salts, and hydrogen peroxide are most popular oxygen-release materials. This paper mainly summarized the research progress of three types of oxygen-releasing materials at home and abroad.

关 键 词：组织工程 氧气释放 局部氧疗 伤口敷料 过氧化氢 

分 类 号：TB324[一般工业技术—材料科学与工程]