干眼动物模型制备规范(草案)  

Specifications for Preparation of Dry Eye Animal Models (Draft)

作　　者：中药实验药理专业委员会 Traditional Chinese Medicine Experimental Pharmacology Professional Committee;China Association of Chinese Medicine

机构地区：[1]中华中医药学会中药实验药理专业委员会

出　　处：《中国实验方剂学杂志》2018年第19期6-9,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家“十一五”科技支撑计划项目(2008BAI53B09);国家中医药管理局中医药标准化专项(2017-149-11);国家自然科学基金项目(81173474)

摘　　要：干眼是临床最为常见的一种眼科疾病,其主要表现为眼部干涩、流泪、异物感以及视物模糊、视力疲劳等。目前干眼发病机制尚不明确,现有干眼动物模型主要是病理模型,且以西医指标为主。基于对干眼中西医临床病证特点的分析及对其现有动物模型的大量实验研究,形成了如下干眼动物模型制备规范（草案）,为该模型的相关研究提供参考。Dry eye is one of the most common ophthalmic diseases in clinic. Its main manifestations are dry eyes,tears,foreign body sensation,blurred vision,asthenopia and so on. At present,the pathogenesis of dry eye is uncertain,the present dry eye animal model is mainly pathological model,and mainly based on western medicine indicators. Based on the analysis of the characteristics of clinical symptoms of Chinese and western medicine in dry eye and the large number of experimental studies on the existing animal models,this article forms the following specifications（ draft） for the preparation of dry eye animal models.

关 键 词：干眼 动物模型 规范 草案 苯扎氯铵 第三眼睑 泪膜破裂时间 

分 类 号：R24[医药卫生—中医临床基础] R22[医药卫生—中医学]