经皮激光汽化减压术联合臭氧注射治疗腰椎间盘突出症的临床观察  

Observation on Clinical Efficacy Percutaneous Laser Disc Decompression in Combination with Ozone Injection of Treating Lumbar Disc Herniation

作　　者：赵继荣[1] 薛旭 陈文[1] 赵宁[1] 朱宝 赵生鑫 马同[2] 王国慧 郭培尧 ZHAO Jirong;XUE Xu;CHEN Wen;ZHAO Ning;ZHU Bao;ZHAO Shengxin;MA Tong;WANG Guohui;GUO Peiyao(Gansu Provincial Hospital of Traditional Chinese Medicine,Lanzhou 730050,China;Gansu University of Traditional Chinese Medicine,Lanzhou 730030,China.)

机构地区：[1]甘肃省中医院,兰州730050 [2]甘肃中医药大学

出　　处：《中国中医骨伤科杂志》2018年第9期23-27,共5页Chinese Journal of Traditional Medical Traumatology & Orthopedics

基　　金：甘肃省自然科学基金资助项目(1606RJZA346)

摘　　要：目的:观察经皮激光汽化减压术(PLDD)联合臭氧注射治疗腰椎间盘突出症(LDH)的临床疗效。方法:以本院2014年10月至2016年9月收治的62例LDH患者作为研究对象,并将所有患者随机分为治疗组和对照组,每组各31例,治疗组给予PLDD联合臭氧注射治疗,对照组给予单纯的PLDD治疗,所有患者于术前、术后1d,1个月,3个月,6个月和12个月,采用视觉模拟疼痛评分法(VAS)评价疼痛缓解程度;Oswestry功能障碍指数问卷表(ODI)评价腰椎功能改善情况;术后12个月采用改良的Macnab疗效标准评价临床疗效。结果:两组患者术前VAS疼痛评分和ODI评分比较,差异无统计学意义(P>0.05);治疗组术后1d,1个月,3个月,6个月及12个月VAS疼痛评分和ODI评分均低于对照组,差异有统计学意义(P<0.05);各组内术后不同时间点的VAS疼痛评分和ODI评分与术前比较差异有统计学意义(P<0.05);时间因素与分组因素存在交互效应分别为(F=4.598,P=0.036)及(F=5.145,P=0.023);术后随访12个月改良的Macnab疗效比较,治疗组优良率为93.55%,对照组优良率为80.65%,差异有统计学意义(P<0.05).结论:PLDD联合臭氧注射治疗椎间盘突出症疗效显著,值得临床推广应用。Objective：To observe the clinical efficacy of percutaneous lasers disk decompression（PLDD）combined with Ozone injection in the treatment of lumbar disc herniation（LDH）.Methods：62 cases of LDH patients treated in our hospital from October 2014 to September 2016 were selected as the research object,all the patients were randomly divided intotreatment group and control group,31 cases in each group.The treatment group was given PLDD combined with Ozone injection,while the control group was given simple PLDD.All of the patients were used Visual analogue scale（VAS）、Oswestry disability index（ODI）in the preoperative and postoperative 1 d,1 month,3 month,6 month and 12 month for the assessment of pain and lumbar function,and useing the modified Macnab criteria was evaluated the clinical efficacy of 12 months after the operation.Results：There was no significant difference in preoperative VAS pain scores and ODI scores between the two groups（P〈0.05）.The VAS pain scores and ODI scores of the treatment group in the postoperative 1 d,1 month,3 month,6 month and 12 month were significantly lower than those of the control group（P〈0.05）.The VAS pain scores and ODI scores of different time points in each group were statistically significant（P〈0.05）.The interaction effects of time and group factors are respectively（F=4.598,P=0.036）,（F=5.145,P=0.023）.After follow-up of 12 months modified Macnab efficacy comparison,the excellent rate of treatment group was 93.55%,while those of controlgroup was 80.65% and the difference were statistically significant（P〈0.05）.Conclusion：PLDD combined with ozone injection is effective in the treatment of lumbar disc herniation,and it is worthy of clinical application.

关 键 词：经皮激光汽化减压术 臭氧注射 腰椎间盘突出症 疗效 

分 类 号：R681.5[医药卫生—骨科学]