超重及肥胖与盆腔器官脱垂发生风险关系Meta分析  

Association of overweight and obesity with incidence of pelvic organ prolapse:a Meta-analysis study

作　　者：毛巧玲[1] 周全[1] 黄凤[1] 黄分 全丹丹[1] 佐满珍[1] MAO Qiao-ling;ZHOU Quan;HUANG Feng;HUANG Fen;QUAN Dan-dan;ZUO Man-zhen(The People＇s Hospital of China Three Gorges University ＆ the First People＇s Hospital of Yichang,Yichang 443000,China)

机构地区：[1]三峡大学人民医院(宜昌市第一人民医院),湖北宜昌443000

出　　处：《中国实用妇科与产科杂志》2018年第9期1030-1034,共5页Chinese Journal of Practical Gynecology and Obstetrics

基　　金：国家自然科学基金青年基金项目(81401187)

摘　　要：目的探讨超重、肥胖与盆腔器官脱垂(POP)发生风险的相关性。方法采用系统评价方法,计算机检索Pubmed、Embase、Cochrane Library数据库,检索时间均从建库至2017年7月,纳入关于超重、肥胖与POP发生风险的队列研究和病例对照研究。2名评价者独立选择文献、提取资料、评价质量并交叉核对后,用Stata12.0软件进行Meta分析。结果最终纳入6个病例对照研究及9个队列研究,Meta分析结果显示:与正常体重人群相比,超重和肥胖人群的POP发病风险均明显增高(超重:OR=1.25,95%CI 1.15~1.37,P=0.00;肥胖:OR=1.44,95%CI 1.31~1.58,P=0.00)。结论超重、肥胖均能增加POP的发病风险。Objective To study the correlation of overweight and obesity with incidence of pelvic organ prolapse（POP）.Methods We searched Pub Med,Embase and Cochrane Library database from their inception to July 2017,including the cohort studies and case-control studies on the correlation of overweight and obesity with incidence of POP,in a systematic evaluation way.The studies were screened by two researchers independently,the quality was evaluated,the data were extracted,and then Meta-analysis was performed using Stata 12.0 software.Results Six case-control studies and nine cohort studies were included finally.The results of Meta-analysis showed that,compared with the normal weight population,the incidence of POP was obviously higher in the overweight population（OR=1.25,95%CI 1.15~1.37,P=0.00）,and obese population（OR=1.44,95%CI 1.31~1.58,P=0.00）.Conclusion Overweight and obesity can increase the incidence of POP.

关 键 词：超重 肥胖 盆腔器官脱垂 META分析 

分 类 号：R711.5[医药卫生—妇产科学]