植入前遗传学诊断及筛查技术的实验室质量控制体系  

Quality management of preimplantation genetic diagnosis and preimplantation genetic screening

作　　者：黄锦[1] 加加林 王云[1] 乔杰[1] Huang Jin, Jia Jialin, Wang Yun, Qiao Jie(Reproductive Medical Centre, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, Chin)

机构地区：[1]北京大学第三医院妇产科生殖医学中心,100191

出　　处：《中华生殖与避孕杂志》2018年第8期643-646,共4页Chinese Journal of Reproduction and Contraception

摘　　要：近年来,随着分子生物学和辅助生殖技术(ART)的进步,胚胎植入前遗传学诊断(PGD)和胚胎植入前遗传学筛查(PGS)技术以其前所未有的速度在全球快速发展。本文从胚胎活检和遗传学诊断这2个方面,对PGD/PGS的实验室建立、人员培训及操作流程等方面做一综述,并提出了质量控制的具体评价指标。In recent years, with the development of molecular biology and assisted reproductive technology （ART）, preimplantation genetic diagnosis （PGD） and preimplantation genetic screening （PGS） have been improved dramatically in the world. In this review, we summarized the quality management of preimplantation genetic diagnosis and preimplantation genetic screening, such as laboratory establishment, staff training and operation process from the two aspects of embryo biopsy and genetic diagnosis. Moreover, we put forward specific evaluation indicators for quality management.

关 键 词：胚胎植入前遗传学诊断(PGD) 胚胎植入前遗传学筛查(PGs) 质量控制 

分 类 号：R714.8[医药卫生—妇产科学]