独脚金的化学成分研究  

Chemical constituents of Striga asiatica(L.)O.K.

作　　者：钟凤娥 李胜华[2] 江贤方 张良勇 ZHONG Feng＇e;LI Shenghua;JIANG Xianfang;ZHANG Liangyong(Huaihua Forestry Research Institute,Huaihua 418008,China;Key Laboratory of Hunan Province for Study and Utilization of Ethnic Medicinal Plant Resources,Huaihua 418008,China)

机构地区：[1]怀化市林业科学研究所,湖南怀化418008 [2]民族药用植物资源研究与利用湖南省重点实验室,湖南怀化418008

出　　处：《湖南林业科技》2018年第5期63-67,72,共6页Hunan Forestry Science & Technology

摘　　要：为研究玄参科植物独脚金(Striga asiatica(L.)O.K.)全草的化学成分,采用硅胶柱色谱、凝胶色谱等方法进行化学成分的分离纯化,通过理化性质和波谱数据(如核磁共振、红外光谱、质谱等)进行结构鉴定。结果表明:分离鉴定了到19个化合物,分别为(-)-threo-guaiacyl-glycerol-8-O-4'-(coniferyl alcohol) ether(1),3β-hydroxyolean-12-en-11-one acetate(2),2α, 3α, 19α, 23-四羟基-乌索烷-12-烯-28-O-β-D-葡萄糖苷(3),olean-12-ene-3β,7β,15α,28-tetraol(4),黄芩素6,4'-二甲醚(5),金圣草黄素(6),金圣草黄素-7-O-葡萄糖苷(7),rhamnopyranosyl vanilloyl(8),5, 3', 4'-三羟基-3,7-二甲氧基黄酮(9),5,7,3',4',5'-五甲氧基黄酮(10),木犀草素-7, 3', 4'-三甲醚(11),芹菜素(12),芹菜素-7-O-β-D-葡萄糖醛酸甲酯(13),芹菜素-7-O-β-D-葡萄糖醛酸苷(14),3-O-(6'-O-palmitoy-β-D-glucosyl)-spinasta-7,22-diene(15),木犀草素-7-O-β-D-葡萄糖苷(16),槲皮素-3-O-β-D-吡喃葡萄糖苷(17),withagulatin A(18),(6S,9R)-roseoside(19),其中化合物1,2,3,4和19是首次从该属植物中分离得到。To study the chemical constituents of Striga asiatica（L.）O.K.,the chemical constituents were isolated and purified with silica column chromato-graphy and gel chromatography,and their structures were identified by physico-chemical properties and various spectroscopic methods including NMR spectrum,MS,UV,etc. The results showed,19 compounds were isolated and elucidated as （-）-threo-guaiacyl-glycerol-8-O-4＇-（coniferyl alcohol） ether （1）,3β- hydroxyolean-12-en-11-one acetate（2）,2α,3α,19α,23-tetrahydroxy-ursa-12-en-28- oicacid-28-O-β-D-glucopyranosylester（3）,olean-12-ene-3β,7β,15α,28-tetraol（4）,scutellain-6,4＇-dimethy ether（5）,chrysoeriol（6）,chrysoeriol-7-O-glucoside（7）,rhamnopyranosyl vanilloyl（8）,5,3＇,4＇-trihydroxy-3,7-dimethoxyflavone（9）,5,7,3＇,4＇,5＇- pentamethoxyflavone（10）,luteolin-7,3＇,4＇-trimethyl ether（11）,apigenin（12）,apigenin- 7-O-β-D-glucuronide methyl ester（13）,apigenin-7-O-β-D- glucopyranuro -nide（14）,3-O-（6＇-O-palmitoy-β-D-glucosyl）-spinasta-7,22-diene（15）,luteolin-7-O-β-D-glucoside（16）,quercetin-3-O-β-D-glucopyr-anoside（17）,withagulatinA（18）,（6S,9R）-roseoside（19）.The compound 1,2,3,4 and 19 are isolated from the plant of genus for the first time.

关 键 词：独脚金 化学成分 withagulatin A 

分 类 号：R284.1[医药卫生—中药学]