肺结核患者营养风险和营养指标相关性分析  

Correlation analysis between nutritional risk and nutrition-related parameters in patients with pulmonary tuberculosis

作　　者：谢雯霓[1] 邓国防[2] 施汶言 吕卉 吴晶[1] Xie Wenni;Deng Guofang;Shi Wenyan;Lyu Hui;Wu Jing(Department of Clinical Nutrition,the Third Peoples Hospital of Shenzhen,Shenzhen 518112,China)

机构地区：[1]深圳市第三人民医院临床营养科,深圳518112 [2]深圳市第三人民医院肺病二科,深圳518112

出　　处：《新医学》2018年第10期740-744,共5页Journal of New Medicine

基　　金：深圳市卫生计生系统科研项目(201507025)

摘　　要：目的对不同类型肺结核病患者的营养风险和营养相关指标进行分析,以指导营养支持治疗。方法对407例肺结核患者使用营养风险筛查2002(NRS 2002)工具进行评估,收集身高、体质量、BMI、白蛋白、血红蛋白、淋巴细胞绝对值(LYMPH)和CRP,分析不同类型肺结核病的营养风险和营养指标及其之间的关系。结果入组407例患者中,营养风险发生率为50. 1%,老年肺结核病患者营养风险发生率(64. 2%)较年轻患者高(48. 0%,P <0. 05); NRS 2002得分和BMI、白蛋白、血红蛋白、LYMPH分别呈负相关,和CRP呈正相关(P均<0. 05);肺结核组的白蛋白、血红蛋白和LYMPH高于肺结核合并其他结核病组(合并其他结核病组),CRP低于合并其他结核病组(P均<0. 05);肺结核组和合并其他结核病组营养风险发生率分别为49. 8%和50. 5%(P> 0. 05),耐药结核病组(耐药组)营养风险发生率为62. 1%,与非耐药结核病组(非耐药组)的49. 2%相比有升高趋势但差异无统计学意义(P> 0. 05)。结论 NRS 2002和营养指标具有相关性,肺结核患者无论有无合并其他结核病、是否耐药结核病,都应常规接受综合营养评估。Objective To analyze the correlation between nutritional risk and nutrition-related parameters in the patients with different types of pulmonary tuberculosis （TB）, aiming to guide the nurtition support therapy. Methods A total of 407 patients with pulmonary TB received Nutritional Risk Screening 2002 （NRS 2002） to assess the nutritional risk. Height, weight, body mass index （BMI）, serum albumin count （ALB）, hemoglobin （HGB）, peripheral blood lymphocyte count （LYMPH） and C-reactive protein （CRP） were collected to analyze the relationship between nutritional risk and nutrition-related parameters in patients with different types of pulmonary TB. Results Among all cases, 50.1% of TB patients were at nutritional risk. The incidence rate of nutritional risk in the elderly group was 64.2%, significantly higher than 48.0% in the young group （P 〈 0.05）. The NRS 2002 score was negatively correlated with BMI, ALB, HGB and LYMPH, whereas positively associated with CRP （all P 〈 0.05）. In the pulmonary TB group, ALB, HGB and LYMPH were all significantly higher, whereas CRP level was considerably lower than those in the pulmonary TB complicated with other types of TB group （all P 〈 0.05）. The incidence rate of nutritional risk rate in the pulmonary TB group was 49.8%, and the pulmonary TB complicated with other types of TB group was 50.5% （P〉0.05）. The incidence rate of nutritional risk in the drug-resistant TB group was 62.1%, a little higher than 49.2% in the non-resistant TB group with no statistical significance （P〉0.05）. Conclusions NRS 2002 is correlated with nutrition-related parameters. Patients with pulmonary TB should receive regular comprehensive nutritional assessment regardless of whether they are complicated with other types of TB or drug-resistant TB.

关 键 词：肺结核 营养风险筛查 营养指标 

分 类 号：R521[医药卫生—内科学]