宫颈癌患者化疗相关认知障碍与负性情绪及疲乏的相关性  

Correlations of cognitive impairments following chemotherapy with fatigue, anxiety and depression in cervical cancer survivors

作　　者：黄慧玲 罗艳华 张扬 曾迎春[3] 韩媛 Huang Huiling;Luo Yanhua;Zhang Yang;Zeng Yingchun;Han Yuan(Shaoguan Yuebei People＇s Hospital,Shaoguan,512026;School of Science,Guangzhou Medical University,Guangzhou,510010;The Third Affiliated Hospital Guangzhou Medical University,Guangzhou,510150,China)

机构地区：[1]广州医科大学附属韶关粤北人民医院,广东韶关512026 [2]广州医科大学护理学院,广东广州510010 [3]广州医科大学附属第三医院,广东广州510150

出　　处：《现代临床护理》2018年第7期14-18,共5页Modern Clinical Nursing

基　　金：广东省医学科研基金项目;项目编号为A2015141

摘　　要：目的了解宫颈癌患者化疗相关认知障碍(chemotherapy-related cognitive impairment,CRCI)发生情况及其与负性情绪、疲乏的相关性。方法采用癌症治疗功能评估—认知功能量表(functional assessment of cancer therapy-cognitive funtion,FACT-Cog)、医院焦虑抑郁量表(hospital anxiety and depression scale,HADS)、简明疲乏量表(brief fatigue inventory,BFI-C)对106例宫颈癌化疗患者进行调查。结果 106例宫颈癌患者CRCI发生率为30.19%,FACT-Cog总分(104.14±21.48)分;焦虑症状总分(11.42±4.37)分;抑郁症状总分(11.74±4.22)分;BFI-C总分(30.58±21.87)分。宫颈癌患者FACTCog总分及其维度得分与焦虑、抑郁、疲乏得分均呈负相关(P<0.05,P<0.01)。结论宫颈癌患者CRCI发生率较高,焦虑、抑郁及疲乏处于中度水平;CRCI与焦虑、抑郁及疲乏存在相关性。应重视宫颈癌患者CRCI发生情况,加强情绪和疲乏症状的评估和管理有助于患者CRCI的预防和缓解。Objective To evaluate the prevalence and its relationship to anxiety, depression and fatigue in women with cervical cancer. Method A functional assessment of cancer therapy-cognitive function （FACT-Cog）, hospital anxiety and depression scale （HADS）, Chinese version of the brief fatigue inventory （BFI-C） were used to study 106 patients with cervical cancer. Results The incidence of chemotherapy related cognitive impairment（CRCI ） in 106 patients with cervical cancer was 30.19%, with total FACT-Cog score （104.14 ± 21.48） and the total score of anxiety symptoms was 11.42±4.37. The total score on depressive symptoms was （11.74±4.22） with a total fatigue score of 30.58_＋21.87. FACT-Cog score and dimension score of cervical cancer patients were negatively correlated with anxiety, depression and fatigue （P〈0.05, P〈0.01）. Conclusions The incidence of CRCI is high in cervical cancer patients, with mild levels of anxiety and depression and moderate levels of fatigue. CRCI was associated with anxiety, depression and fatigue. Attention should be paid to the occurrence of CRCI in cervical cancer patients, and the assessment and management of emotional and fatigue symptoms should be strengthened to help patients prevent and relieve CRCI.

关 键 词：宫颈癌 化疗相关认知障碍 焦虑 抑郁 疲乏 

分 类 号：R473.73[医药卫生—护理学]