双源CT对无症状糖尿病患者冠状动脉病变及左心功能的研究  

Study of dual-source CT in evaluating the coronary artery disease and left ventricular function of asymptomatic diabetes patients

作　　者：田培刚[1] 李明志[1] 郑向阳[1] 于艳妮[2] 张显鹏[3] TIAN Peigang;LI Mingzhi;ZHENG Xiangyang;YU Yanni;ZHANG Xianpeng(Radiation Protection Safety Institute,Shandong Center for Disease Control and Prevention,Jinan,250014,China.)

机构地区：[1]山东省潍坊市中医院影像中心,山东潍坊261000 [2]山东省潍坊市人民医院超声科,山东潍坊261000 [3]山东省疾病预防控制中心辐射防护安全所,山东济南250014

出　　处：《中国中西医结合影像学杂志》2018年第5期455-458,共4页Chinese Imaging Journal of Integrated Traditional and Western Medicine

基　　金：潍坊市卫生计生委科研项目(2016WSJS113)

摘　　要：目的 :利用双源CT冠状动脉造影(DSCTA)探讨无症状糖尿病患者冠状动脉改变,并通过对比超声心动图,探讨DSCT在评价左心功能中的可行性。方法:选取行DSCTA检查患者80例(无症状糖尿病组40例,非糖尿病组40例),对比分析2组冠状动脉粥样硬化分支数目及钙化积分,以及DSCT与超声心动图所测左心室舒张末期容积(EDV)、收缩末期容积(ESV)及射血分数(EF)值。结果:无症状糖尿病组2支、3支病变数及钙化例数均多于非糖尿病组,而单支病变数少于非糖尿病组(均P<0.05)。DSCT所测无症状糖尿病组的EDV及ESV值大于非糖尿病组,而EF值小于非糖尿病组(均P<0.05)。DSCT所测左心功能各项指标(EDV、ESV、EF)与超声心动图所测数值相关性高,差异均无统计学意义(均P> 0.05)。结论:无症状糖尿病患者较非糖尿病患者易发生广泛的冠状动脉粥样硬化,且心功能出现一定程度降低;DSCT能早期发现无症状糖尿病的冠状动脉及左心功能改变,可用于糖尿病患者冠状动脉硬化性心脏病的早期筛查。Objective：To investigate the coronary artery disease of asymptomatic diabetes patients by dual-source CT coronary angiography （DSCTA）,and explore the feasibility of DSCT in evaluating the left ventricular function compared with ultrasonic cardiogram. Methods：80 patients,including 40 cases of asymptomatic DM and 40 cases of non-DM,underwent coronary DSCTA.The number of atherosclerotic coronary artery and the calcification score in asymptomatic DM group and non-DM group were contrast analyzed,as well as EDV,ESV,EF of the left ventricular between coronary DSCTA and ultrasonic cardiogram. Results：Cases of double-vessel or three-vessel lesion and calcification in asymptomatic DM group were more than those in non-DM group,while single vessel disease cases were less （all P〈0.05）. The EDV,ESV measured by DSCT were higher in asymptomatic DM group than that in non-DM group,while EF was lower,the differences were statistically significant （all P〈0.05）. Discrepancy of the left ventricular function index （EDV,ESV,EF） between coronary DSCTA and ultrasonic cardiogram had no statistically significance （all P〉0.05）. Conclusion：It prones to extensive coronary atherosclerosis in asymptomatic DM patients than non-DM patients,and the left ventricular function in asymptomatic DM patients has been reduced in some extent. DSCT can early detect the change of coronary artery and left ventricular function in asymptomatic DM patients. It can be used for screening for diabetic coronary artery diseases.

关 键 词：糖尿病 冠状动脉疾病 体层摄影术 X线计算机 心室功能 左 

分 类 号：R541.4[医药卫生—心血管疾病] R587.1[医药卫生—内科学] R816.2[医药卫生—临床医学]