基于空芯微结构光纤拉曼探针的实验研究  

Raman probe based on hollow-core microstructured fiber

作　　者：盛子城 王腾 周桂耀[1] 夏长明[1] 刘建涛[1] 李波瑶 樊海霞 陈云[1] 侯峙云[1] Sheng Zi-Cheng;Wang Teng;Zhou Gui-Yao;Xia Chang-Ming;Liu Jian-Tao;Li Bo-Yao;Fan Hai-Xia;Chen Yun;Hou Zhi-Yunt(Cuangdong Provice Key Laboratory of Nano-photonic Functional Materials and Devices,South China Normal University,Guangzhou 510006,China)

机构地区：[1]华南师范大学,广东省微纳光子功能材料与器件重点实验室,广州510006

出　　处：《物理学报》2018年第18期166-171,共6页Acta Physica Sinica

基　　金：国家自然科学基金(批准号：61575066)、国家自然科学基金重点项目(批准号：61735005);国家自然科学基金仪器专项基金(批准号：61527822); 广东省科技计划(批准号：2017KZ010101); 广东省高等学校珠江学者岗位计划资助项目(2017)资助的课题

摘　　要：表面增强拉曼散射(SERS)技术可有效增强样品分子的拉曼信号,对生物分子检测具有较高的灵敏性,因此在生化方面有着许多潜在的应用.而将空芯微结构光纤与SERS技术相结合不仅能够远端实时、分布式地检测,同时还可以增加光场与待测物的有效作用面积,减少传统光纤探针无法避免的石英背景信号等问题.本文基于空芯微结构光纤进行SERS探针的制备及性能测试研究,利用真空物理溅射法在空芯光纤内镀纳米Ag膜,从而制备成SERS探针,通过实验检测不同浓度的罗丹明6G (R6G)酒精溶液的拉曼信号.结果表明,在探针的近端正面成功探测到了浓度低至10^(-9)mol/L的R6G拉曼信号,在探针的远端反面探测到的浓度可小于10^(-6)mol/L.该实验结果为研究高灵敏度的SERS探针提供了一种新的手段.Surface-enhanced Raman scattering（SERS） technology can effectively enhance the Raman signal of sample molecules. It has a higher sensitivity to detect biomolecule and thus has many potential applications in biochemistry. The combination of hollow-core microstructured fiber and SERS technology not only enables remote real-time and distributed detection, but also can increase the effective action area between the light field and the object to be measured, and further reduce silica glass background signal that is unavoidable in traditional fiber probes. In this paper, the hollow-core microstructure fiber Raman probes with excellent performance are investigated from the aspects of fiber preparation and SERS experi-mental testing. First, we design and manufacture a kind of hollow-core microstructured fiber with multi-bands in the visible and near-infrared wavelength. The fibers show good light guide performance and thus can fully meet the requirements for surface-enhanced Raman excitation and signal transmission.At the same time, the large core size facilitates the coupling of excitation light, and provides enough room for the test object and the light field. Then, this hollow-core microstructured fiber is used in surface-enhanced Raman experiment. A layer of nano-Ag film is modified on the inner surface of the hollow-core microstructure fiber to prepare the SERS probe by the vacuum physical sputtering method, and Rhodamine 6 G（R6 G） alcohol solutions with different concentrations are prepared by the dilution method. The hollow-core microstructured fiber deposited with the Ag nanofilm is immersed in R6G alcohol solution for 2 min. The alcohol solution of R6 G is sucked into the air hole of the hollow-core microstructured fiber by the capillary effect. Then this fiber with R6 G alcohol solution is placed in a drying oven at 40？C for 3 h until the alcohol solvent in the air hole is completely volatilized. After that, this fiber is taken out and tested under a detection environment full with air. The fiber SERS

关 键 词：空芯微结构光纤 表面增强拉曼 光纤探针 

分 类 号：TN253[电子电信—物理电子学]