Formation and Biomimetic Deposition of Bone-like Hydroxyapatite on Wollastonite-gypsum Composites  

作　　者：Yaser Greish Nuha Attia Abdel-Hamid Mourad 

机构地区：[1]Department of Chemistry, College of Science, United Arab Emirates University, AI Ain, UAE [2]Department of Ceramics, National Research Centre, Cairo, Egypt [3]Department of Mechanical Engineering, College of Engineering, United Arab Emirates University, Al Ain, UAE [4]Mechanical Design Department, Faculty of Engineering at Mataria, Helwan University, Cairo, Egypt

出　　处：《Journal of Bionic Engineering》2018年第5期894-906,共13页仿生工程学报（英文版）

摘　　要：Bone cements are often used for bone repair and fixation. The main objective of formulating a bone cement is to achieve structure and properties similarity to bone. In addition, bioactivity of a bone cement provides a major advantage that helps achieving better binding and interaction with the surrounding tissues. In the current study, gypsum was used as a matrix for a composite that comprises highly crys- talline prestine and acid-treated wollastonite （CaSiO3） fibers. Composites made by mixing their powder precursors with deionized water at room temperature, were investigated for their composition using X-ray diffraction （XRD） and Thermogravimetric Analysis （TGA）, for their microstructure using Scanning Electron Microscopy （SEM）, for their compressive strengths and modulus of elasticity, and for setting time measurements. In addition, cement composites were evaluated for their preliminary bioactivity in a protein-free Simulated Body Fluid （SBF） for up to 14 days. Results show the improvement of mechanical properties and bioactivity of the composites using acid-treated wollastonite fibers. This was attributed to the formation of hydrated silica layer on the surface of the acid-treated fibers which improved the binding with the gypsum matrix and provided nucleating sites for the deposition of bone-like apatite spherolites from SBF media.Bone cements are often used for bone repair and fixation. The main objective of formulating a bone cement is to achieve structure and properties similarity to bone. In addition, bioactivity of a bone cement provides a major advantage that helps achieving better binding and interaction with the surrounding tissues. In the current study, gypsum was used as a matrix for a composite that comprises highly crys- talline prestine and acid-treated wollastonite （CaSiO3） fibers. Composites made by mixing their powder precursors with deionized water at room temperature, were investigated for their composition using X-ray diffraction （XRD） and Thermogravimetric Analysis （TGA）, for their microstructure using Scanning Electron Microscopy （SEM）, for their compressive strengths and modulus of elasticity, and for setting time measurements. In addition, cement composites were evaluated for their preliminary bioactivity in a protein-free Simulated Body Fluid （SBF） for up to 14 days. Results show the improvement of mechanical properties and bioactivity of the composites using acid-treated wollastonite fibers. This was attributed to the formation of hydrated silica layer on the surface of the acid-treated fibers which improved the binding with the gypsum matrix and provided nucleating sites for the deposition of bone-like apatite spherolites from SBF media.

关 键 词：GYPSUM WOLLASTONITE bone cement BIOMIMETIC SBF microstructure 

分 类 号：TQ172.4[化学工程—水泥工业] TS251.94[化学工程—硅酸盐工业]