检索规则说明:AND代表“并且”;OR代表“或者”;NOT代表“不包含”;(注意必须大写,运算符两边需空一格)
检 索 范 例 :范例一: (K=图书馆学 OR K=情报学) AND A=范并思 范例二:J=计算机应用与软件 AND (U=C++ OR U=Basic) NOT M=Visual
作 者:潘雯 丁晶 汪昕 Pan Wen;Ding Jing;Wang Xin(Department of Pharmacy,Zhongshan Hospital,Fudan University,Shanghai 200032,China)
机构地区:[1]复旦大学附属中山医院药剂科,上海200032 [2]复旦大学附属中山医院神经内科,上海200032
出 处:《中华神经科杂志》2018年第9期758-762,共5页Chinese Journal of Neurology
摘 要:抗癫痫药和抗感染药经常需要联合运用,它们之问有临床意义的相互作用可能导致药物不良反应或治疗失败。我们通过病例报道、作用机制等方面综述了抗癫痫药与常用抗感染药的相互作用,包括:大环内酯类药与卡马西平,碳青霉烯类药与丙戊酸钠,三唑类抗真菌药与卡马西平、苯妥英钠、苯巴比妥,抗结核药与苯妥英钠、地西泮、卡马西平、奥卡西平,抗寄生虫药吡喹酮和阿苯达唑与苯妥英钠、卡马西平、苯巴比妥的组合。而新型抗癫痫药物,例如奥卡西平、拉莫三嗪、托吡酯、左乙拉西坦等,与抗感染药物少见有临床意义的相互作用。Antiepileptic drugs and anti-infective drugs are prescribed at the same time in many cases. The clinically important interactions between them may lead to adverse reaction or failure of treatment. We summarize these clinically important interactions with case reports and mechanism of action. The combinations include macrolides and carbamazepine, carbapenems and valproic acid, ciprofloxaein and carbamazepine, phenytoin, triazole antifungal agents and carbamazepine, phenytoin, and phenobarbital, antituberculosis drugs and phenytoin, diazepam, carbamazepine and oxearbazepine, anthelminfic drugs and phenytoin, carbamazepine and phenobarbital. While new antiepileptic drugs used in China like oxcarbazepine, lamotrigine, topiramate and levetiracetam have little clinically important interaction with anti- infective drugs.
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在链接到云南高校图书馆文献保障联盟下载...
云南高校图书馆联盟文献共享服务平台 版权所有©
您的IP:216.73.216.33