HFpEF虚实证候的临床检查指标分析  

Analysis of Clinical Examination Indicators among HFp EF Patients with Deficiency and Excess Syndrome

作　　者：王金平 刘俊杰 王佩佩 张飞龙 贾彩霞 高阔[1] 陈建新[1] 王娟[1] 赵慧辉[1] 王伟[1] Wang Jinping;Liu Junjie;Wang Peipei;Zhang Feilong;Jia Caixia;Gao Kuo;Chen Jianxin;Wang Juan;Zhao Huihui;Wang Wei(Beijing University of Chinese Medicine,Beijing 100029,China)

机构地区：[1]北京中医药大学,北京100029

出　　处：《世界中医药》2018年第9期2127-2129,2135,共4页World Chinese Medicine

基　　金：国家重点研发计划资助(2017YFC1700100)--"气虚证辨证标准的系统研究";中央高校基本科研业务费专项资金资助项目(2017-JYB-XS-101)--"基于ACE2-Ang1-7-MasR轴抗心肌纤维化研究芪参颗粒对心衰的保护作用"

摘　　要：目的:本研究通过分析射血分数保留的心衰(Ejection Fraction Reserved for Heart Failure,HFp EF)患者虚实证候的临床检查指标,探讨HFp EF虚实证候临床检查指标的特征。方法:通过横断面调查研究,收集射血分数保留的心力衰竭患者的一般临床信息与血液检测指标及超声心动等临床检查指标,采用Logistic回归等方法对不同证候HFp EF患者的临床检查指标进行分析。结果:以临床诊断HFp EF虚实证候为因变量,将差异有统计学意义的客观检查指标进行二元逐步Logistic回归分析,最终留在方程中的是心率(Heart Rate,HR)与射血分数(Ejection Fraction,EF)。结论:射血分数保留的心力衰竭中,HR和EF与患者的虚实证候关系密切。Objective： To analyze the clinical examination indicators of heart failure with preserved ejection fraction（ HFp EF） patients with deficiency and excess syndrome to explore the characteristics. Methods： Through cross-sectional investigation,general clinical information,blood test and echocardiogram indexes of patients with HFp EF were collected. Then Logistic regression was used to analyze the clinical examination indicators of HFp EF patients with different syndromes. Results： With the syndrome of HFp EF patients as the dependent variable,a binary Logistic regression analysis was performed on the indicators with statistically significant differences,and the final remaining variables were the heart rate（ HR） and the ejection fraction（ EF）. Conclusion： In patients with heart failure with ejection fraction retention,HR and EF are closely related to deficiency and excess syndrome.

关 键 词：射血分数保留的心力衰竭 证候 虚实 二元LOGISTIC回归 超声心动 

分 类 号：R2-03[医药卫生—中医学]