中药含漱液应用于神经内科危重患者的疗效观察  

Observation on Therapeutic Effects of Chinese Medicine Gargle on Critically Ill Patients of Neurology

作　　者：齐馨馨 李小秦 李家伟 姚明 雷明 Qi Xinxin;Li Xiaoqin;Li Jiawei;Yao Ming;Lei Ming(Department of Critical Medicine,Puren Hospital of Wuhan,Wuhan 430081,China;Department of Neurology,General hospital of the Yangtze river shipping,Wuhan 430010,China)

机构地区：[1]湖北省武汉市普仁医院重症医学科,武汉430081 [2]武汉长江航运总医院神经内科,武汉430010

出　　处：《世界中医药》2018年第9期2200-2202,2206,共4页World Chinese Medicine

基　　金：长航局重点科技项目(20171001)

摘　　要：目的:探讨中药含漱液应用于神经内科危重患者的疗效方法:选取2016年9月至2017年9月武汉市普仁医院重症医学科收治的神经内科危重患者82例,按照随机数字表法分为观察组(n=42)和对照组(n=40)。对照组给予0.9%氯化钠溶液含漱水治疗,观察组给予中药含漱液进行治疗,2组均以14天为1个疗程,共治疗1个疗程。观察2组患者口腔细菌菌落以及口腔相关疾病发生率。结果:治疗前2组患者口腔细菌菌落数比较,差异无统计学意义(P>0.05),治疗后2组口腔细菌菌落数较治疗前均减少,差异有统计学意义(P<0.05),观察组改善口腔细菌菌落数疗效明显优于对照组(P<0.05);观察组口腔异味和口腔溃疡发生率明显低于对照组(P<0.05);观察组口腔干裂和肺部感染发生率虽然低于对照组,但差异无统计学意义(P>0.05)。结论:中药含漱液能抑杀口腔细菌的生长,防治神经内科危重患者口腔异味及口腔溃疡发生率效果显著。Objective： To investigate the curative effects of Traditional Chinese Medicine （TCM） gargle in oral cavity of critically ill patients of neurology. Methods： A total of 82 critically ill patients with neurological treated in Department of Critical Medicine in Puren Hospital of Wuhan from September 2016 to September 2017 were selected and divided into observation group （ n =42） and control group （ n =40） according to random table method.The control group was given 0.9% sodium chloride solution rinse water,and the observation group was given TCM gargle （the main ingredients were Radix Rehmanniae Recens,Radix Scrophulariae,Radix Ophiopogonis,Radix Glehniae,Rhizoma Coptidis,Radix Sophorae Flavescentis,Radix Ilicis Asprellae,Herba GynoStemmae Pentaphilli）.Oral bacterial colonies and the incidence of oral-related diseases in both groups were observed. Results： There was no significant difference in the number of bacterial colonies in both groups before and after treatment （ P 〉0.05）.The number of bacterial colonies in the oral cavity before and after treatment in both groups significantly decreased,which had statistical significance （ P 〈0.05）.The observation group was significantly better than the control group in improving the number of bacterial colonies in the oral cavity （ P 〈0.05）.The incidence of oral malodor and oral ulcer in the observation group was significantly lower than that of the control group （ P 〈0.05）.Although the incidence of dry fracture of the mouth and pulmonary infection in observation group was lower than that of the control group,the difference was not statistically significant （ P 〉0.05）. Conclusion： TCM gargle can inhibit oral bacteria growth,and it is effective in the prevention and treatment of critical patients with neurological disorders of oral odor,which is worth promoting.

关 键 词：中药含漱液 神经内科危重患者 口腔疾病 口腔细菌菌落 

分 类 号：R248[医药卫生—中医临床基础]