2015-2016年青海省HIV抗体初筛阳性样本确证结果分析  

Confirmatory analysis of HIV screening postive samples in Qinghai Province from 2015 to 2016

作　　者：吴建英[1] 贾清[1] 石林飞 马韶辉[1] WU Jianying;JIA Qing;SHI Linfei;MA Shaohui(Qinghai Center for Disease Control and Prevention,Xining 810007,China)

机构地区：[1]青海省疾病预防控制中心,西宁810007

出　　处：《医学动物防制》2018年第10期1003-1005,共3页Journal of Medical Pest Control

基　　金：中央补助地方公共卫生专项资金项目(青卫疾控[2011]41号)

摘　　要：目的分析2015-2016年青海省HIV抗体筛查结果,为掌握青海省艾滋病的流行现状和趋势提供支持。方法对2015-2016年青海省908份HIV抗体筛查阳性标本采用蛋白免疫印迹实验(Western blot,WB)进行确证,并用SPSS 19.0进行统计分析。结果 908份筛查阳性标本中,确证HIV-1阳性672份,占74.01%;阴性175份,占19.27%;不确定61份,占6.72%。疾控机构、医疗机构、采供血机构确证阳性率分别为94.72%、68.33%、50.48%,疾控机构筛查阳性样本的准确率最高。在确证阳性样本中,男性标本556份,女性标本116份,男女比例约为4.8∶1,男性发病主要集中于20~59岁,占91.55%(509/556);女性发病主要集中于20~49岁,占88.79%(103/116)。结论青海省HIV感染者多见于青年和中年,且男性多于女性。HIV抗体初筛试验结果存在一定的假阳性,通过WB确证实验可以排除筛查实验中的假阳性。Objective To analysise the confirmatory results of HIV antibody screening positive samples in Qinghai Province from 2015 to 2016, and to provide support for understanding the current situation and the epidemic trends of AIDS in this province. Methods 908 HIV antibody screening positive samples were confirmed by Western blot test （WB） from 2015 to 2016, and the statistical analysis was performed by SPSS 19.0. Results Of the 908 screening positive samples, HIV-1 antibody confirmed positive rate was 74.01% （672/908） , the negtive rate being 19.27% （175/908） , and the uncertain rate was 6.72% （61/908）. The positive rates of confirmation from disease control institutions, medical institutions and blood collection and blood supply institutions were 94.72%, 68.33% and 50.48% respectively, and the accuracy rate of screening positive samples was the highest in CDC. In confirmed positive samples, the male to female ratio was about 4.8 1（556/116）. The onset age of male patients weres mainly 20～59 years, accounting for 91.55% （509/556）, however, the female patients were mainly 20～49 years, accounting for 88.79% （103/116）. Conclusion HIV infection in Qinghai Province is more common among young people and middle-aged people, and the infection rate of male is higher than that of female. There are some false results in the HIV antibody screening tests, and the false positives in screening tests can be ruled out by WB confirmated.

关 键 词：HIV 筛查 免疫印迹实验 

分 类 号：R512.91[医药卫生—内科学]