香茶菜属植物二萜和五味子降三萜合成进展  

Recent Advances in the Synthesis of Isodon Diterpenoids and Schinortriterpenoids

作　　者：颜秉超 胡坤 孙汉董[1] 普诺.白玛丹增 Yan Bingchao,Hu Kun,Sun Handong,Puno Pematenzin(a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 65020)

机构地区：[1]中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,昆明650201

出　　处：《有机化学》2018年第9期2259-2280,共22页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.81673329)资助项目~~

摘　　要：香茶菜属植物和五味子科植物是两大重要的药用植物类群,而香茶菜属植物二萜和五味子降三萜的研究则是近年来天然产物研究领域具有代表性研究成果之一.目前,从香茶菜属植物中已发现1200多个二萜类化合物,涉及11种结构类型;而从五味子科植物中已发现200多个五味子降三萜(schinortriterpenoids,SNTs),包括二十余种不同骨架类型.由于其多样的结构类型和显著的生物活性引起了国内外合成化学家的广泛关注.对近十年来香茶菜属植物二萜和五味子降三萜的合成进行综述.The plants of the genus Isodon and the schisandraceae family are two economically and medicinally important phytogroups, and the research of chemical constituents from these two phytogroups has been recognized as one of the most outstanding achievements in natrural product research recently. So far, over 1200 diterpenoids classified into 11 different groups have been reported from the Isodon species and more than 200 schinortriterpenoids（SNTs） involving more than 20 skeletons have been isolated from the schisandraceae species. Their diverse scffolds and significant bioactivities have aroused great interest among the community of organic synthetic chimistry. In this review, the advances in the synthesis of Isodon diterpenoids and schinortriterpenoids during the past decade will be reviewed.

关 键 词：香茶菜属 二萜 五味子科 五味子降三萜 合成 

分 类 号：O629[理学—有机化学] TQ460.1[理学—化学]