突发性聋30例精神心理状况分析  

Assessment of psychopathological characteristics in 30 patients with sudden sensorineural hearing loss

作　　者：朱文燕[1] 金新[1] 佘万东[2] 马永驰[1] ZHU Wenyan;JIN Xin;SHE Wandong;MA Yongchi(The Affiliated Huaian First People＇s Hospital of Nanjing Medical University,Huaian 223300,Jiangsu,China;Drum Tower Hospital Affiliated to Nanjing University,Nanjing 210008,Jiangsu,China)

机构地区：[1]南京医科大学附属淮安第一医院,江苏淮安223300 [2]南京大学附属鼓楼医院,江苏南京210008

出　　处：《山东大学耳鼻喉眼学报》2018年第5期50-52,共3页Journal of Otolaryngology and Ophthalmology of Shandong University

摘　　要：目的初步了解突发性聋患者的精神心理状况。方法对30例突发性聋患者(突聋组)及20例健康对照成人(对照组)进行90项症状自评量表(SCL-90)心理学测试及血浆中5-羟色胺(5-HT)检测。结果突聋组SCL-90总分为(121.69±22.53)分,总均分为(1.35±0.25)分,对照组SCL-90总分为(111.65±15.25)分,总均分为(1.23±0.25)分。突聋组SCL-90总分及总均分与对照组比较,P均>0.05。但突聋组躯体化、抑郁、偏执和其他(睡眠、饮食等)这四个因子分均高于对照组(P均<0.05)。突聋组5-HT含量较对照组降低(P<0.05),SCL-90评分与血浆5-HT水平呈负相关(r=-0.507,P=0.004)。结论突发性聋患者较正常人有轻度心理精神障碍倾向,存在明显抑郁、偏执及睡眠等障碍,且5-HT含量较正常人明显减少。Objective To investigate the psychopathological characteristics of patients with sudden sensorineural hearing loss（ SSHL）. Methods The Symptom Checklist-90（ SCL-90） scores and plasma 5-hydroxytryptamine（ 5-HT） levels were determined in 30 patients with SSHL and 20 healthy adult controls. Results The total and average SCL-90 scores were 121. 69 ± 22. 53 and1.35±0.25,respectively,in the SSHL group,and 111. 65 ± 15. 25 and 1. 23 ± 0. 25 in the control group. There were no significant differences in total and average scores between the two groups（ P〉0.05）. However,the SCL-90 scores for the four dimensions of somatization,depression,paranoia,and other（ sleep,diet,etc.） were higher in the SSHL group than in the control group,and the difference was statistically significant（ P〈0.05）. The plasma 5-HT level in the SSHL group was significantly lower than in the normal control group（ P〈0. 05） and the SCL-90 score was negatively correlated with the plasma 5-HT（ r =-0. 507,P = 0. 004）.Conclusion Compared with healthy adults,patients with SSHL showa tendency toward mild psychopathology. Patients with SSHL have clear evidence of depression,paranoia,and sleep disorders,and significantly lower plasma 5-HT levels compared to healthy adults.

关 键 词：突发性聋 精神心理 抑郁 90项症状自评量表 5-羟色胺 

分 类 号：R764.437[医药卫生—耳鼻咽喉科]