纤维支气管镜治疗AECOPD合并严重呼吸衰竭的临床研究  

Effects of fiber bronchoscope in treatment of AECOPD complicated with severe respiratory failure

作　　者：谭红梅[1] 谭春梅[2] 冯晓丽[1] 潘彬[1] Tan Hongmei;Tan Chunmei;Feng Xiaoli;Pan Bin(Depamnent of Respiratory Medicine,the First Affiliated Hospital of Chengdu Medical College,Chengdu,Siehuan,610500,China;Depamnent of Obstetrics,the First Affiliated Hospital of Chengdu Medical College,Chengdu,Siehuan,610500,China)

机构地区：[1]成都医学院第一附属医院呼吸内科,成都610500 [2]成都医学院第一附属医院产科,成都610500

出　　处：《西南国防医药》2018年第10期919-921,共3页Medical Journal of National Defending Forces in Southwest China

摘　　要：目的探讨纤维支气管镜治疗慢性阻塞性肺疾病急性发作(AECOPD)合并呼吸衰竭的疗效。方法回归性分析84例AECOPD合并呼吸衰竭的患者,根据治疗方式不同分为对照组(n=42,予以常规治疗)与观察组(n=42,予以常规治疗+纤维支气管镜治疗),对比两组治疗前后动脉血气分析指标、无创正压通气时间、痰标本合格率及阳性率。结果治疗后,两组动脉血气分析指标较治疗前有明显好转,且观察组改善程度更大(P <0.05)。在治疗期间,观察组的痰标本合格率为97.62%,阳性率为80.95%,而对照组分别为76.19%和54.76%,两组差异显著(P <0.05)。观察组无创正压通气时间明显短于对照组(P <0.05)。结论对AECOPD合并呼吸衰竭的患者,在常规治疗的基础上,采用纤维支气管镜联合治疗,能够提高采集痰标本的合格率,有效改善患者摄氧,促进恢复,提高临床疗效。Objective To explore the effects of fiber bronehoseope in the treatment of acute exacerbation of chronic obstructive pulmonary disease （AECOPD） complicated with respiratolT failure. Methods Regression analysis was conducted on 84 patients with AECOPD complicated with respiratory failure. These patients were divided into a control group （n=42, treated with conventional therapy） and an observation group （n=42, treated with conventional therapy ＋fiber bronehoseope therapy） according to different therapies. The arterial blood gas analysis index, non-invasive positive pressure ventilation time and sputum pass rate and positive rate before and after the treatment were eompared between the two groups. Results After the treatment, there was a significant improvement in the arterial blood gas analysis index in the two groups eompared with that before the treatment, and the improvement in the observation group was greater （P 〈 0.05）. During the treatment, the sputum pass rate in the observation group was 97.62% and the positive rate 80.95%, while those in the control group were 76.19% and 54.76% respectively, showing significant differences （P 〈 0.05）. The non-invasive positive pressure ventilation time in the observation group was much shorter than that in the control grou （P 〈 0.05）. Conclusion For patients with AECOPD complicated with respiratory failure, on the basis of conventional therapy, the combination with fiber bronehoseope therapy can improve the pass rate of the sputum samples collected, effectively improve the patient oxygen uptake, promote the recovery and improve the effects.

关 键 词：纤维支气管镜 慢性阻塞性肺疾病 急性发作 呼吸衰竭 疗效 

分 类 号：R563[医药卫生—呼吸系统]