口服补液疗法对新生儿高胆红素血症蓝光治疗中肝肠循环效果的影响  

Effect of Oral Rehydration Therapy on the Hepato-enteric Circulation in the Blue Light Therapy for Neonatal Hyperbilirubinemia

作　　者：李亚辉 洪梅[1] 滕高菁 韦玉华[2] 韦秀珍[2] LI Ya-hui;HONG Mei;TENG Gao-jing;WEI Yu-hua;WEI Xiu-zhen(Department of Pediatrics,Guangxi Zhuang Autonomous Region Riverside Hospital,Nanning,Guangxi,530021 China;Department of Pediatrics,Guangxi Zhuang Autonomous Region People＇s Hospital,Nanning,Guangxi,530021 China)

机构地区：[1]广西壮族自治区江滨医院儿科,广西南宁530021 [2]广西壮族自治区人民医院儿科,广西南宁530021

出　　处：《系统医学》2018年第16期184-186,共3页Systems Medicine

基　　金：广西壮族自治区卫生厅自筹经费科研课题(合同号Z2013361)

摘　　要：目的探讨口服补液疗法对新生儿高胆红素血症蓝光治疗中肝肠循环效果的影响。方法选取于2017年1—12月因高胆红素血症来该院就诊病室的患儿120例,按照随机数字法将入组对象随机分为观察组和对照组两组,每组60例,对照组患儿给予奶量130 mL/(kg·d)喂给,1次/3 h;观察组对照组治疗基础上给予3次温开水30 mL/次,对比分析两组患儿在治疗前后出现的血清总胆红素值、尿量、大便量及体重变化。结果观察组治疗后血清总胆红素为(94.12±89.21)μmol/L明显低于对照组的(145.36±51.86)μmol/L,差异有统计学意义(t=6.857,P>0.05)。观察组治疗后尿量为(230.23±51.40)mL明显高于对照组的(196.32±46.71)mL,差异有统计学意义(t=4.881,P<0.05)。观察组治疗后大便量为(52.31±19.47)g明显高于对照组的(40.57±13.74)g,差异有统计学意义(t=4.835,P<0.05)。结论给予光疗的患儿喂给温开水简单易行,不会给患儿增加痛苦,还可适当补充摄入量,加速患儿胆红素排出。Objective To study the effect of oral rehydration therapy on the hepato-enteric circulation in the blue light therapy for neonatal hyperbilirubinemia. Methods 120 cases of children diagnosed in our ward with hyperbilirubinemia in our hospital from January to December 2017 were selected and randomly divided into two groups with 60 cases in each, the control group were fed with 130 mL/（kg·d） milk, 1/3 h, while the observation group were given the warm boiled water 30 ml each time for three times, and the serum total bilirubin, urine volume, stool volume and body weight changes before and after treatment were compared and analyzed. Results After treatment, the serum total bilirubin was obviously lower than that in the control group, [（94.12±89.21）μmol/L vs（145.36±51.86）μmol/L], and the difference was statistically significant（t=6.857, P0.05）. After treatment, the urine volume in the observation group was obviously higher than that in the control group, [（230.23±51.40）mL vs（196.32±46.71）mL], and the difference was statistically significant（t=4.881,P0.05）. After treatment, the stool volume in the observation group was obviously higher than that in the control group,[（52.31 ±19.47） g vs（40.57±13.74）g], and the difference was statistically significant（t=4.835,P 0.05）.Conclusion The warm boiled water for children with phototherapy is simple without increasing pains for children, but also properly supplement the intake and accelerate the bilirubin discharge of children.

关 键 词：新生儿高胆红素血症 肝肠循环 口服补液方法 

分 类 号：R722.17[医药卫生—儿科]