儿童艾滋病101例临床分析  

Clinical Analysis of 101 Children with AIDS

作　　者：周继敏[1,2] 石艳儿 黄寅朔 Zhou Jimin;Shi Yan;Huang Yinshuo(Department of Pediatrics,the First People＇s Hospital of Liangshan Prefecture,Xichang,Sichuan 615000,China)

机构地区：[1]凉山州第一人民医院儿科,四川西昌615000 [2]凉山州第一人民医院预防保健科,四川西昌615000

出　　处：《四川医学》2018年第9期999-1002,共4页Sichuan Medical Journal

摘　　要：目的了解儿童艾滋病的临床特征,尽早发现并诊断儿童艾滋病。方法回顾性分析四川省凉山州第一人民医院2012年2月至2018年2月收治的101例儿童艾滋病临床资料。结果儿童HIV感染主要通过母婴垂直传播(92. 1%)。常见的临床表现有体重下降、贫血、持续或间断发热、反复咳嗽、迁延性腹泻、浅表淋巴结肿大、鹅口疮等。血生化突出改变主要为球蛋白增高、白球蛋白倒置。结论儿童HIV感染途径以母婴传播为主;临床表现多样,没有特异性,以血液系统最常见,消化系统次之,呼吸系统第三。对于来自高流行地区的患儿,如同时伴有球蛋白增高,应高度警惕HIV感染可能,尽早进行HIV抗体筛查明确诊断。Objective To understand the clinical characteristics of AIDS in children and to detect and diagnose AIDS in children as soon as possible.Methods The clinical data of 101 children with AIDS admitted in Sichuan Liangshan first people’s Hospital from February 2012 to February 2018 were retrospectively analyzed.Results HIV infection in children was mainly transmitted from mother to child（ 92. 1%）.Common clinical manifestations include weight loss,anemia,persistent or intermittent fever,recurrent cough,persistent diarrhea,superficial lymphadenopathy,thrush,etc. The prominent changes of blood biochemistry are mainly the increase of globulin and the inversion of albumin and globulin.Conclusion The main route of HIV infection in children was mother-to-child transmission; the clinical manifestations were diverse and non-specific,among which,the blood system was the most common,the digestive system was the second,and the respiratory system was the third.For children from high epidemic areas,if accompanied by increased globulin,we should be highly alert to the possibility of HIV infection,and make a clear diagnosis of HIV antibody screening as soon as possible.

关 键 词：HIV/ARDS 儿童 临床分析 母婴垂直传播 

分 类 号：R512.91[医药卫生—内科学]