陕西省1018例HIV/AIDS病人HBV、HCV及TP合并感染情况  

Analysis of 1 018 HIV/AIDS patients co-infected with HBV,HCV,and TP in Shaanxi

作　　者：张超[1] 李华[1] 任强[1] 邹扬帆[1] 付钰淋[1] 张梦妍[1] 常文辉[1] ZHANG Chao;LI Hua;REN Qiang;ZOU Yangfan;FU Yulin;ZHANG Mengyan;CHANG Wenhui(Department of AIDS Prevention and Control,Shaanxi Province Center for Disease Control and Prevention,Xi＇an,Shaanxi 710054,China)

机构地区：[1]陕西省疾病预防控制中心艾滋病预防控制所,陕西西安710054

出　　处：《中国热带医学》2018年第10期999-1003,共5页China Tropical Medicine

基　　金：陕西省疾病预防控制重大课题(No.2014A5)

摘　　要：目的分析陕西省艾滋病病毒(HIV)感染者/艾滋病(AIDS)病人(简称HIV/AIDS病人)中,乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)及梅毒螺旋体(TP)共感染情况,为陕西省HIV防控提供科学依据。方法对陕西省HIV/AIDS病人进行横断面调查,采用酶联免疫吸附试验(ELISA)进行乙肝五项、抗-HCV及抗-TP检测。结果 1 018例HIV/AIDS病人中,112例(11.0%)乙肝表面抗原(HBsAg)阳性,共发现19种血清模式,其中以HBsAb单阳最高,446例(43.8%),其次为HBV标志物全阴,307例(30.2%),乙肝"大三阳"(HBsAg+、HBsAb-、HBeAg+、HBeAb-、HBcAb+)16例(1.6%);抗-HCV阳性119例(11.1%);抗-TP阳性265例(26.0%);抗-HCV+抗-TP阳性22例(2.2%),抗-HCV+HBsAg阳性17例(1.7%),抗-TP+HBsAg阳性26例(2.6%),抗-HCV+HBsAg+抗-TP阳性1例(0.1%)。结论陕西省HIV/AIDS人群中HBV、HCV、TP合并感染率高于普通人群,应加强HIV/AIDS人群宣传教育及乙肝疫苗接种工作。Objective To investigate the status of HIV/AIDS patients co-infected with HBV,HCV,and TP, andprovide scientific evidence for HIV prevention and control for HIV/AIDS patients in Shaanxi Provence. Methods Aretrospective analysis was carried out for HIV/AIDS patients, and HBV markers, anti-HCV, anti-TP were tested by enzyme-linked immunosorbent assay（ELISA）. Results Of 1 018 HIV/AIDS patients detected by HBV markers, anti-HCV, anti-TP,112 patients（11.0%） were HBsAg positive. 19 kinds of HBV marker＇s phenotype distribution were found. Of which, the highestmodel（HBsAg-, HBsAb＋, HBeAb-, HBeAb-, HBcAb-） were 446 cases（43.8%）, followed by the model（HBsAg-, HBsAb-,HBeAb-, HBeAb-, HBcAb-） which were 307 cases（30.2%）. The model（HBsAg＋、HBsAb-、HBeAg＋、HBeAb-、HBcAb＋）were 16 cases（1.6%）. 119 cases（11.1%）were anti-HCV positive. 265 cases（26.0%）were anti-TP positive. 22 cases（2.2%）were HCV and TP co-infection. 17 cases（1.7%）were HCV and HBV co-infection. 26 cases（2.6%）were TP and HBV co-infection. 1 case（0.1%）was HCV, HBV and TP co-infection. Conclusion The rate of HIV/AIDS patients co-infected withHBV,HCV,TP was higher than that in the general population, and the vaccination work and Health Education Propagandashould be intensified.

关 键 词：艾滋病病毒感染者/艾滋病病人 乙型肝炎病毒 丙型肝炎病毒 梅毒螺旋体 共感染 

分 类 号：R512.91[医药卫生—内科学]