小剂量山莨菪碱佐治婴幼儿肺炎的临床应用研究  

Clinical Study on Low Dose Anisodamine Adjuvant Infantile Pneumonia

作　　者：黄斌[1] Huang Bin(Department of Pediatrics,Pingxiaaag People＇s Hospital,Pingxiang,Jiangxi,337000,China)

机构地区：[1]萍乡市人民医院儿科,江西萍乡337000

出　　处：《当代医学》2018年第29期76-77,共2页Contemporary Medicine

摘　　要：目的探究小剂量山莨菪碱佐治婴幼儿肺炎的临床应用效果。方法选取2016年1月～2017年12月在本院收治的60例婴幼儿肺炎患儿作为研究对象,采用随机住院病历单双号法分为试验组(n=30)和基础组(n=30),基础组给予常规抗感染、止咳、化痰、吸氧治疗,试验组则在此基础上联合给予0.1～0.3 mg的小剂量山莨菪碱进行治疗,观察对比其临床疗效。结果与基础组相比较,试验组患儿咳嗽、喘息气促以及肺部湿啰音等临床体征消失时间明显缩短,组间数据比较差异具有统计学意义(P<0.05)。试验组治疗总效率与基础组相比较差异具有统计学意义(P<0.05)。结论针对肺炎患儿,在常规抗感染对症治疗的基础上配合小剂量山莨菪碱进行辅佐治疗疗效更确切,可快速缓解肺部临床症状,减少肺部湿啰音,具有一定的安全性和可行性,推广价值高。Objective To explore the clinical application effect of small dose ofanisodamine in the treatment of infant pneumonia. Methods From January 2016 to December 2017, 60 cases of infantile pneumonia in our hospital were selected as the study objects. The patients were randomly divided into two groups： the experimental group （n 30） and the basic group （n 30）. The basic group was given routine anti-infection. The experimental group was treated with small dose of anisodamine 0.1-0.3 mg on the basis of cough, phlegm and oxygen inhalation, and the clinical effect was ob- served and compared. Results Compared with the basic group, the time of the clinical signs such as cough, wheezing, and lung wet luo were significantly shortened in the experimental group, and there was a difference in the data between the groups （P〈0.05）. The difference of total therapeutic efficiency between the experimental group and the basic group was statistically significant （P〈0.05）. Conclusion In view of the infant pneumonia in children, on the basis of routine anti-infection symptomatic treatment with small dose of adjuvant scopolamine for the treatment curative effect more precise, can quickly relieve the clinical symptoms, lung reduce lung wet rale, has certain feasibility, safety and high promotion value.

关 键 词：小剂量 山莨菪碱 婴幼儿肺炎 临床应用 

分 类 号：R725.6[医药卫生—儿科]