Macleaya cordata helps improve the growth-promoting effect of chlortetracycline on broiler chickens  

博落回辅助性地提高金霉素在肉鸡生长促进中的作用（英文）

作　　者：Bin LI Jin-qiu ZHANG Xian-gan HAN Zheng-lei WANG Yuan-yuan XU Jin-feng MIAO 

机构地区：[1]Key Laboratory of Animal Physiology and Biochemistry, College of Veterinary Medicine,Nanjing Agricultural University [2]National Research Center for Veterinary Vaccine Engineering and Technology of China,Jiangsu Academy of Agricultural Sciences [3]Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences

出　　处：《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2018年第10期776-784,共9页浙江大学学报（英文版）B辑（生物医学与生物技术）

基　　金：Project supported by the Natural Science Foundation of Jiangsu Province for Excellent Young Scholars(No.BK20170087);the National Natural Science Foundation of China(Nos.31502033,31472164,and 31672515)

摘　　要：Chlortetracycline （CTC）, one kind of common antibiotic for prevention and treatment of various diseases, also exhibits good performance in accelerating the growth of livestock. Macleaya cordata, a traditional Chinese medicine, is usually used as a natural additive in livestock because of its anti-microbial, anti-fungal, anti-inflammatory, and pesticidal activity. In this work, we studied whether M. cordata helps regulate the growth-promoting effect of CTC on broiler chickens. It is demonstrated that M. cordata improves the growth-promoting effect of CTC on growth per- formance indices of broiler chickens, such as survival rate, daily weight, and feed to weight rate. M. cordata also delays the maximum of CTC residues in plasma. It may depend on the higher values of operational taxonomic unit （OTU） and the indices of o diversity driven by simultaneous use of CTC and M. cordata.目的:通过同时与金霉素饲喂,验证博落回在肉鸡生长促进中的作用。创新点:通过博落回与金霉素的同时饲喂改进肉鸡生长,优化肉鸡表观指标的同时,检测体内金霉素残留,提高肉鸡饲养的经济利益。方法:在肉鸡饲养过程中记录体重和采食量等基础数据,通过换算并比较存活率、日增重及料重比,进行肉鸡生长表观指标的比较;在给药饲喂过程中以及结束后,采取动物的组织及血液,通过高效液相色谱法和高效液相色谱-串联质谱法检测金霉素含量,同时应用16S测序检测饲喂后十二指肠肠道微生物菌群组成结构。结论:证实博落回虽然增加了肝脏中金霉素残留量,但可以通过调节十二指肠肠道微生物菌群来提高金霉素的促生长作用。

关 键 词：CHLORTETRACYCLINE Macleaya cordata Broiler chicken Growth promotion Gut flora 

分 类 号：S831.5[农业科学—畜牧学]