经皮椎体成形术治疗椎体重度压缩性骨折合并囊性改变的临床疗效  

Clinical effect of percutaneous vertebroplasty for severe osteoporotic vertebral body compression fractures combined with intraosseous vacuum phenomena

作　　者：王福安 吕朋华 王书祥 孙陵 徐川 黄文诺 耿素萍 张勤 何仕诚[2] Wen Fuan;Lyu Penghua;Wang Shuxiang;Sun Ling;Xu Chuan;Huang Wennu;Geng Suping;Zhang Qin;He Shichen(Department of Interventional Radiology,Clinical Medical College of Yangzhou University,Yangzhou 225001,China;Department of Interventional Radiology cald Vascular Surgery,Zhongda Hospital,Southeast University,Nanjing 210009,China.)

机构地区：[1]苏北人民医院(扬州大学临床医学院)介入放射科,江苏扬州225001 [2]南京中大医院(东南大学附属医院)介入与血管外科,江苏南京210009

出　　处：《中华介入放射学电子杂志》2018年第4期311-314,共4页Chinese Journal of Interventional Radiology：electronic edition

摘　　要：目的:探讨经皮椎体成形术(PVP)治疗骨质疏松重度压缩性骨折合并椎体囊性改变患者的临床疗效。方法:选取2006年9月至2017年12月我院收治的25例重度压缩性骨折合并椎体囊性改变患者,均采用PVP进行治疗,分析PVP手术成功率,术后24 h、1周及1、3、6、12个月分别随访患者疼痛情况并记录有效率。采用卡方检验比较各个时期的疼痛缓解有效率。结果:所有患者均成功接受PVP手术,手术成功率100%。手术时间25～45 min,平均32 min;出血量1～5 ml,平均2.4 ml;骨水泥填充量为4.5～20 ml,平均8.6 ml。25例中除1例患者因冠心病于术后10个月死亡外,其余24例均完成第12个月随访。术后24 h、1周及1、3、6和12个月的疼痛缓解有效率分别为72%(18/25)、64%(16/25)、68%(17/25)、76%(19/25)、76%(19/25)和70.8%(17/24),差异无统计学意义(χ~2=1.326,P>0.05)。结论:PVP治疗严重的骨性椎体椎体压缩骨折合并椎体囊性改变是安全有效的。Objective： To investigate the clinical efficacy of percutaneous vertebroplasty （PVP） in the treatment of severely compressed bone fractures with intraosseous vacuum phenomena. METHODS： From September 2006 to December 2017, 25 cases of severe compression fracture combined with intraosseous vacuum phenomena received PVP treatment. The clinical data of these patients were retrospectively analyzed. The success rate of PVP procedure was analyzed, and regular follow-up was conducted after the operation. Pain relief rate was recorded. RESULTS： All patients completed PVP operation under local anesthesia, and two patients received repeat PVP three days later due to poor pain relief effect. Postoperative pain assessment was followed up 24 hours, 1 week, 1, 3, 6 and 12 months, and the effective rate was recorded. The effective rates were 72 percent （18/25）, 64 percent （16/25）, 68 percent （17/25）, 76 percent （19/25）, 76 percent （19/25） and 70.8 percent （17/24）, respectively. Chi-square test showed no significant difference in pain symptoms at each time check point. CONCLUSION： PVP is a safe and effective treatment for severe bone vertebral compression fractures intraosseous vacuum phenomena.

关 键 词：经皮椎体成形术 椎体压缩性骨折 重度 囊性改变 骨质疏松 

分 类 号：R687.3[医药卫生—骨科学]