水突穴体表电刺激联合耳穴贴压治疗围绝经期综合征临床疗效观察  

Observation of the clinical effects on perimenopausal syndrome treated with the transcutaneous electrostimulation at Shuitu(ST 10) and the seed-pressure therapy at the auricular points

作　　者：闫学花[1] 陈书英[1] 闫利荣[1] 苏心镜[2] YAN Xuehua;CHEN Shuying;YAN Lirong;SU Xinjing(Department of Gynecology;Department of Pain,the Second Affiliated Hospital of Hebei North College,Zhangjiakou 075100,China)

机构地区：[1]河北北方学院附属第二医院妇产科,张家口075100 [2]河北北方学院附属第二医院疼痛科,张家口075100

出　　处：《中国针灸》2018年第10期1065-1069,共5页Chinese Acupuncture & Moxibustion

摘　　要：目的:比较水突穴体表电刺激联合耳穴贴压与激素替代疗法治疗围绝经期综合征(PMS)患者临床疗效。方法:PMS患者64例,根据患者本人的意愿,分为观察组(30例)和对照组(34例)。观察组采用水突穴体表电刺激联合耳穴贴压,水突穴刺激强度为15~20 m A,刺激时间为20 min,每周2次,8次为一疗程,共3个疗程;耳穴贴压取内分泌、神门、卵巢、子宫、肝、肾,每周贴压1次,保留5 d,4周为一疗程,共3个疗程。对照组采用激素替代治疗,从月经来潮第5天开始口服戊酸雌二醇片1 mg,每天1次,连用21 d;于口服戊酸雌二醇片的第12天开始口服地屈孕酮片20 mg,每天1次,连用10 d,共3个疗程。观察两组患者治疗前、治疗结束后1、3个月围绝经期患者主要症状评分(Kuppermann评分)、性激素(卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E2))水平及不良反应情况。结果:治疗后1、3个月,两组Kuppermann评分较治疗前显著降低(均P<0.05),两组血清FSH、LH水平较治疗前明显下降(均P<0.05),血清E2水平较治疗前明显上升(均P<0.05);治疗后组间以上指标比较差异均无统计学意义(均P>0.05)。对照组阴道出血、乳房胀痛、子宫内膜增厚不良反应发生率均高于观察组(17.6%(6/34)vs 0%(0/30),20.6%(7/34)vs 3.3%(1/30),8.8%(3/34)vs 0%(0/30),均P<0.05)。结论:水突穴体表电刺激联合耳穴贴压治疗围绝经期综合征的疗效与激素替代疗法相当,能有效改善临床症状和性激素水平,并且不良反应和并发症明显少于激素替代疗法。Objective To compare the differences in the clinical therapeutic effects on perimenopausal syndrome（PMS） between the combined treatment with the transcutaneous electrostimulation at Shuitu（ST 10） and the seed-pressure therapy at the auricular points and the hormone replacement therapy. Methods A total of 64 PMS patients were divided into an observation group（30 cases） and a control group（34 cases） according to patient＇s willingness. In the observation group, the transcutaneous electrostimulation at Shuitu（ST 10） was combined with the seed-pressure therapy at the auricular points. The stimulation intensity at Shuitu（ST 10） was ranged from 15 to 20 m A, for 20 min in each treatment, twice a week. The 8 treatments made one course and 3 courses were required. Additionally, the seed-pressure therapy was used at neifenmi（CO18）, Shenmen（TF4）, luanchao, zigong, gan（CO12）, shen（CO10）, once a week, retained for 5 days. The 4-week treatment was as one course and a total of 3 courses were required. In the control g roup, the hormone replacement therapy was applied. On Day 5 of menstruation, progynova was prescribed for oral administration, 1 mg, once a day, continuously for 21 days. On Day 12 in the oral administration of progynova, dydrogesterone was used, 20 mg, once every day, continuously for 10 days. Totally, 3 courses were required. Separately, before treatment and in 1 and 3 months after treatment, Kuppermann score, the sexual hormone levels [follicle-stimulating hormone（FSH）, luteinizing hormone（LH） and estradiol（E2）] and the adverse reactions were observed in the patients of the two groups. Results In 1 and 3 months after treatment, Kuppermann scores were reduced significantly as compared with those before treatment in the two groups（all P〈0.05）. The levels of serum FSH and LH were reduced remarkably as compared with those before treatment in the two groups（all P〈0.05） and the level of serum E2 was increased remarkably as compared with that before tre

关 键 词：围绝经期综合征 体表电刺激 穴 水突 耳穴贴压 绝经症状评分 性激素 不良反应 

分 类 号：R246.3[医药卫生—针灸推拿学]