生物质木质素磺酸催化合成N-取代吡咯（英文）  

Synthesis of N-Substituted Pyrroles using Lignosulfonic Acid as Biomass-Based Catalyst

作　　者：代红光[1] 刘旭慧 王丽荣[1] 师兰 Dai Hongguang;Liu Xuhui;Wang Lirong;Shi Lan(College of Science,hmer Mongolia Agricultural University,Hohhot 010018)

机构地区：[1]内蒙古农业大学理学院,呼和浩特010018

出　　处：《化学通报》2018年第10期929-933,共5页Chemistry

基　　金：国家自然科学基金项目(21607085)资助

摘　　要：木质素磺酸是非均相、环境友好的生物质催化剂。本文以造纸废料木质素磺酸钠为原料,通过离子交换的方法制备了木质素磺酸。通过红外、元素分析、滴定等方法表征了木质素磺酸的结构。以木质素磺酸为催化剂,2,5-己二酮与伯胺发生Paal-Knorr反应以较优的产率合成了N-取代吡咯。伯胺的亲核能力越强,反应越容易进行,是典型的亲核反应。Lignosulfonic acid is a kind of heterogeneous, environmentally friendly, biomass-based solid catalyst. In this paper,it was prepared by ion-exchange method using sodium lignosulfonate in papermaking waste as raw material. Its structure was characterized by FT-IR,elemental analysis and titration. Using lignosulfonic acid as a catalyst,N-substituted pyrroles were synthesized efficiently by Paal-Knorr reaction of hexane-2,5-dione and primary amine in good to excellent yields. This is a typical nucleophilic reaction. The stronger the nucleophilic ability of the primary amine,the more easily the reaction proceeds.

关 键 词：Paal-Knorr反应 木质素磺酸 吡咯 生物质催化剂 

分 类 号：O626.13[理学—有机化学]