改性二氧化硅/纳米银微粒的制备及其抗菌性能分析  

Preparation of modified silica/silver nanoparticles and its antibacterial properties

作　　者：林家洪 宋天龙 刘永龙 杨娟 疏秀林[3] 李文茹[3] 陈娟 邱晓颖 施庆珊[1,2,3] LIN Jiahong;SONG Tianlong;LIU Yonglong;YANG Juan;SHU Xiulin;LI Wenm;CHEN Juan;QIU Xiaoying;SHI Qingshan(Guangdong Demay Biologieal Teehnology Co.,Ltd,Guangzhou 510663 China;Guangdong Province antimicrobial Engineering Teehnology Research Center,Guangzhou 510070,China;Guangdong Institute of Mierobiology,State Key Laboratory of Applied Microbiology Southern China,Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application,Guangzhou 510070,China)

机构地区：[1]广东迪美生物技术有限公司,广州510663 [2]广东省防霉抗菌工程技术研究中心,广州510070 [3]广东省微生物研究所省部共建华南应用微生物国家重点实验室广东省菌种保藏与应用重点实验室,广州510070

出　　处：《工业微生物》2018年第5期19-22,共4页Industrial Microbiology

基　　金：广州市科技计划项目(201604016096);广州市珠江新星项目(201610010032)

摘　　要：本文研究了改性二氧化硅包裹纳米银微粒的制备及其形貌的表征分析,通过扫描电镜表征得改性二氧化硅/纳米银微球的形貌规整,粒径主要分布于250 nm～400 nm之间。其次,通过抑菌圈实验测试了改性二氧化硅/纳米银微球对大肠杆菌和金黄色葡萄球菌的抑菌圈大小为18. 5mm和17. 8 mm。此外,将改性二氧化硅添加到人造大理石中,添加量为1. 0%时,其抗菌活性值达3. 0以上。In this paper, the preparation of modified silica coated silver nanoparticles and the characterization of its morphology were investigated. The morphology of the modified silica / silver nanoparticles was regular by scanning electron microscopy （SEM）. The particle size of modified silica/ silver nanoparticles was mainly distributed in the range of 250 nm and 400 nm. Secondly, the bacteriostatic zone sizes of modified silica / silver nanoparticles to Escherichia coli and Staphylococcus attretts were measured to be 18.5 mm and 17.8 mm, respectively. In addition, the antibacterial activity of modified silica added to artificial marble was over 3.0 when the content of modified silica was 1.0%.

关 键 词：纳米银 二氧化硅 改性微粒 抗菌性能 

分 类 号：TB383.1[一般工业技术—材料科学与工程] TB34