18F-FDG PET/CT在MRI阴性癫痫中的诊断价值  

Diagnostic value of 18F-FDG PET/CT in MRI negative epilepsy

作　　者：邵明岩[1] 骆柘璜[1] 徐荣[1] 金爱芳[1] 张慧宁[1] SHAO Mingyan;LUO Zhehuang;XU Rong(Jiangxi Province People＇s Hospital PET/CT Center,Nanchang,330006,China)

机构地区：[1]江西省人民医院PET/CT中心,南昌330006

出　　处：《江西医药》2018年第9期919-921,共3页Jiangxi Medical Journal

基　　金：江西省卫生计生委科技计划;编号20175021

摘　　要：目的探讨18F-FDG PET/CT对MRI阴性癫痫的诊断价值。方法收集我院38例MRI阴性癫痫患者,并均行PET/CT检查。通过视觉分析及半定量分析法,测量SUVmax、AI指数获得癫痫灶的位置及范围,并与术中癫痫灶对比,评价PET/CT对MRI阴性癫痫的诊断价值。结果 38例MRI阴性癫痫患者中,PET/CT诊断阳性30例,诊断阳性率为78.9%。手术25例,与术中定位相符合20例,准确定位率为80%。其中颞叶癫痫18例(海马硬化16例、局灶性皮质发育不全2例),额叶癫痫7例(局灶性皮质发育不全7例)。癫痫灶PET/CT表现均呈放射性摄取均减低,花斑样缺损改变。结论 PET-CT对癫痫灶具有较高的敏感性,对于MRI阴性癫痫,建议行PET/CT检查。Objective In order to explore the diagnostic value of 18F-FDG PET-CT in MRI negative epilepsy. Methods We collected 38 cases of MRI in patients with vaginal epilepsy and performed PET/CT examination. Through visual analysis and semi-quantitative analysis,The position and range of epileptic focus obtained by measuring SUVmax、AI index,and compared with epilepsy in operation to evaluate the diagnostic value of PET/CT on MRI negative epilepsy. Results In the 38 cases of vaginal epilepsy,30 cases were diagnosed as positive by PET/CT,and the positive rate was 78.9%. There were 25 cases of operation,which was in line with 20 cases of intraoperative positioning,and the accurate positioning rate was 80%. Among them,there were 18 cases of temporal lobe epilepsy（16 cases of hippocampus sclerosis,2 cases of focal cortical hypoplasia）,and 7 cases of frontal lobe epilepsy（7 cases of focal cortical hypoplasia）. Epilepsy stoves in PET/CT were all radiolectable decreased,flower spot defect changed. Conclusion PET/CT is highly sensitive to epileptic lesions. For MRI negative epilepsy,PET/CT examination is recommended.

关 键 词：MRI阴性癫痫 癫痫灶定位 发作间期 正电子发射断层计算机扫描 核磁共振 

分 类 号：R817.4[医药卫生—影像医学与核医学]