蒙古族聚居区及蒙汉杂居区乙肝垂直传播阻断免疫效果评价  

Evaluation of Immune Effects of Blocking the Vertical Transmission of Hepatitisb in Mongolian Concentrated Residential Areaand Mongolian and Han Ethnic Minority Areas

作　　者：孙国玉 赵宝林 李树忠 王志广 李佳玉 史建荣 孙冰鑫 宋广华 张明明 马俊清[4] 乔雅威 郭占华 SUN Guo yu;ZHAO Bao lin;LI Shu zhong;WANG Zhi guang;LI Jia yu;SHI Jian rong;SUN Bing xin;SONG Guang hua;ZHANG Ming ming;MA Jun qing;QIAN Ya wei;GUO Zhan hua(Inner Mongolia Family Planning Research Institute,Chifeng 024000 China;Keshiketeng Banner Maternal and Child Health Center of chifeng,jingpeng 025350 China;Yuanbao Mountain Area of Chifeng Maternal and Child Health Hospital,Pingzhuang 024076 China;Chifeng City CDC,chifeng 024000 China)

机构地区：[1]内蒙古计划生育科研所,内蒙古赤峰024000 [2]赤峰市克什克腾旗妇幼保健所,内蒙古经棚025350 [3]赤峰市元宝山区妇幼保健院,内蒙古平庄024076 [4]赤峰市疾病预防控制中心,内蒙古赤峰024000

出　　处：《内蒙古医学杂志》2018年第10期1157-1158,共2页Inner Mongolia Medical Journal

基　　金：内蒙古卫生厅科研项目(201303158)

摘　　要：目的评价蒙古族聚居区及蒙汉杂居区乙肝垂直传播阻断后的免疫效果。方法回顾性总结的方法。筛查试验对象采用普查方法。蒙古族聚居区试验对象为A组,蒙汉杂居区试验对象为B组,对两组试验对象抽取静脉血,应用Colloidal Goid法检测HBsAg、HBsAb、HBcAb、HBeAg、HBeAb。结果 A组HBsAb阳性48例,HBsAb阴性52例,HBsAg、HBcAb、HBeAg、HBeAb均为阴性。B组HBsAb阳性51例,HBsAb阴性49例,HBsAg、HBcAb、HBeAg、HBeAb均为阴性。结论蒙古族集中居住区乙肝阻断后保护性抗体(HBsAb)产生率为48%(48/100),HBsAg阳性者未检出。蒙汉杂居区乙肝阻断后保护性抗体产生率为51%(51/100),HBsAg阳性者未检出。经统计学处理,两组间保护性抗体产生率无显著性差异(χ~2=0.0902,P>0.75)。Objective Evaluate the immunological effect of blocking the vertical transmission of hepatitis b. Method Methods of retrospective summary. The census method was used to screen test subjects. The sub- jects in in Mongolian concentrated residential areaare Group A. The subjects in Mongolian and ban ethnic minori- ty areas are Group B. Venous blood was drawn from the two groups of subjects, using the Colloidal Gold method to detect HBsAg, HBsAb, HBcAb, HBeAg and HBeAb. Results 48 cases of HBsAb were positive in group A, and 52 cases of HBsAb were negative. HBsAg, HBcAb, HBeAg, HBeAb are all negative Group B HBsAb posi- tive 51, HBsAb negative 49. HBsAg, HBcAb, HBeAg, HBeAb are all negative. Conclusion The yield of pro- tective antibody （HBsAb） was 48% （48/100） in group A, and the HBsAg was not detected. The yield of pro- tective antibody in group B was 51 percent （51/100）, and the HBsAg was not detected. There was no signifi- cant difference in the production rate of protective antibody in the two groups（χ^2= 0. 0902, P 〉 0.75）.

关 键 词：乙型病毒性肝炎 垂直传播阻断 免疫效果 

分 类 号：R512.62[医药卫生—内科学]