孕11～14周子宫螺旋动脉彩超预测妊高征的临床研究  

A Clinical Study on the Prediction of Pregnancy-Induced Hypertension Syndron by Color Doppler Ultrasonography in Monitoring Uterine Spiral Blood Flow During in 11～14 Weeks of Pregnancy

作　　者：朱艳芳[1] 杜燕飞 邱燕生[1] 林青梅[1] 罗丽芳[1] 梁翠云 ZHU Yanfang＊;DU Yanfei;QIU Yansheng;LIN Qingmei;LUO Lifang;LIANG Cuiyun(Nanhai Maternity and Child Healthcare Hospital of Foshan,Foshan 528200,China)

机构地区：[1]佛山市南海区妇幼保健院,广东佛山528200

出　　处：《现代医院》2018年第9期1379-1381,共3页Modern Hospitals

基　　金：佛山市科学技术局科研立项(2016AB000802)

摘　　要：目的通过彩色多普勒超声监测孕11～14周子宫螺旋动脉的平均搏动指数(PI)、阻力指数(RI)、收缩期峰值流速与舒张末期血流速度的比值(S/D),探讨孕11～14周子宫螺旋动脉与妊高征的相关性。方法采用前瞻性巢式病例对照研究方法,以2016年4月—2017年4月间在我院产检的孕妇为研究对象,在孕11～14周测量子宫胎盘床螺旋动脉的PI、RI、S/D值,以孕产期被诊断为妊娠高血压综合征的36例孕产妇为病例组,选取同期非妊高征非糖尿病,平时体健,无妇科器质性病变者、不良妊娠及生产史的141例产妇作为对照组,分析两组研究对象子宫胎盘床螺旋动脉相关指标的差异情况。结果孕11～14周妊高征组的子宫螺旋动脉的S/D、PI值与正常妊娠组间无显著性差异(P> 0. 05),而RI值明显高于正常妊娠组(P <0. 01)。结论彩色多普勒超声检测孕11～14周子宫螺旋动脉血流RI值对妊高征的发生发展预测有参考价值。Objective The correlation between uterine spiral artery and pregnancy -induced hypertension syndron in 11 - 14 weeks was discussed by using color doppler ultrasound to monitor the value of PI, RI and S/D of uterine spiral artery in 11 - 14 weeks. Methods A prospective nested case - control study method, in April 2016 - April 2017 in our hos- pital prenatal pregnant women as the research object, measure the uteroplacental bed at 11 - 14 weeks gestation spiral artery PI, RI and S/D value, with maternal diagnosed with pregnancy - induced hypertension syndrome, 36 cases of maternal as case group, select during the same period of pregnancy, high character without diabetes, at ordinary times body health, no organic disease of department of gy-naecology, adverse pregnancy and production history- of 141 cases of maternal as control group, the analysis of two groups of subjects uteroplacental bed differences in related parameters of spiral artery. Results 11 - 14 weeks gestation pregnancy, high character set of uterine spiral artery systolic peak velocity- and end - diastolic blood flow velocity- ratio （S/D）, average pulsation index （PI） and there was no significant difference between normal pregnancy group （ P 〉 0.05 ）, and resistance index （RI） is significantly higher than normal pregnancy group （ P 〈 0.01 ）. Conclusion Color doppler ultrasonography is useful for predicting the occurrence and development of pregnancy - induced hypertension syndron in 11 - 14 weeks.

关 键 词：彩色多普勒 孕11-14周 螺旋动脉 妊高征 

分 类 号：R714.246[医药卫生—妇产科学]