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作 者:樊建 张群跃 李洪晶 刘艳超 关枫[1] 韩凤娟[1] 王艳宏[1] FAN Jian;ZHANG Qunyue;LI Hongjing;LIU Yanchao;GUAN Feng;HAN Fengjuan;WANG Yanhong(Heilongjiang University of Chinese Medicine,Harbin 150040,China)
出 处:《药物评价研究》2018年第9期1730-1737,共8页Drug Evaluation Research
基 金:国家自然科学基金资助项目(81473359);黑龙江省科技厅青年基金项目(QC07C107);黑龙江省教育厅科学技术研究项目(11531357);哈尔滨市应用技术研究与开发项目(RAXXJ047)
摘 要:栓剂是中药传统剂型之一,至今仍在临床中广泛应用,以肛门栓和阴道栓较为普遍。查阅了近年来发表的有关中药肛门栓、阴道栓的文献,结合国家食品药品监督管理总局(CFDA)批准上市的该剂型的新药,进行归纳、分析和总结;综述了复方小儿退热栓、野菊花栓、肛安栓等肛门栓,复方沙棘籽油栓、消糜栓、紫金化毒栓等阴道栓的临床应用、质量控制、制备工艺等研究进展;指出了目前存在的主要问题,以期为中药栓剂的质量提升提供可行性参考。Suppository is one of traditional Chinese medicine dosage forms, which is still used widely in clinic. The anal and the vaginal suppositories are the more commonly used dosage forms. The literatures on anal suppository and vaginal suppository published in recent years combined with the new drug approved by China Food and Drug Administration(CFDA) were analyzed and summarized. The paper reviewed the clinical application, quality control, and preparation technology of anal suppository(Compound Pediatric Antipyretic Suppository, Wild Chrysanthemum Suppository, Gangan Suppository, etc.) and vaginal suppository(Compound Hippophae Rhamnoides Seed Oil Suppository, Anti-cervical Erosion Suppository, Zijin Detoxicating Suppository, etc.). The main problems were pointed out in order to provide a feasible reference for the quality improvement of Chinese herbal suppository.
关 键 词:中药肛门栓 中药阴道栓 复方小儿退热栓 野菊花栓 复方沙棘籽油栓 消糜栓
分 类 号:R282.710.5[医药卫生—中药学]
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