色谱分析法在对复方红藤合剂进行质量控制中的应用价值  

Application value of chromatography in quality control of compound hongteng mixture

作　　者：于良生[1] 纪恒胜[1] 梅涵[1] 赵磊[1] 孟凡刚[1] 杨国帅[1] Yu liangsheng;ji hengsheng;mei han;zhao lei;meng fangang;Yang guoshuai(affiliated hospital of Qingdao university,Qingdao,shandong 26600)

机构地区：[1]青岛大学附属医院,山东青岛266003

出　　处：《当代医药论丛》2018年第17期182-183,共2页

摘　　要：目的 :探讨色谱分析法在对复方红藤合剂进行质量控制中的应用价值。方法 :确定复方红藤合剂的处方组成及制法,采用色谱分析法对其中绿原酸、当归及丹参酮ⅡA等药物成分进行定性鉴别及定量分析。结果 :在对供试样品中的绿原酸、当归进行定性鉴别时发现,在供试样品的色谱中,与对照药材样品色谱相对应的位置上显示出相同颜色的荧光斑点。本试验中各批次样品中丹参酮ⅡA的含量均> 0.41mg/ml。结论 :色谱分析法可用于对复方红藤合剂中的有效成分进行定性鉴别及定量分析,在对复方红藤合剂进行质量控制中的应用价值较高。objective： to explore the application value of chromatography in the quality control of compound hongteng mixture. Methods： to determine the compound prescription sargentgloryvine stem mixture composition and the manufacturing method, using chromatography of chlorogenic acid, angelica and tanshinone Ⅱ A pharmaceutical ingredients such as qualitative identification and quantitative analysis. Results： when the samples were qualitatively identified with chlorogenic acid and angelica sinensis, fluorescence spots of the same color were shown in the chromatogram of the samples. The test samples of each batch of tanshinone Ⅱ A content 0.41 mg/ml. Conclusion： chromatographic analysis can be used for qualitative identification and quantitative analysis of the active ingredients in compound hongteng mixture.

关 键 词：复方红藤合剂 制备 质量标准 

分 类 号：R284.1[医药卫生—中药学]