Functionally graded additive manufacturing to achieve functionality specifications of osteochondral scaffolds  

作　　者：Mario Monzon Chaozong Liu Sara Ajami Miguel Oliveira Ricardo Donate Viviana Ribeiro Rui L. Reis 

机构地区：[1]Departamento de Ingenieria Mecanica, Universidad de Las Palmas de Gran Canaria, Edificio de fabricacion integrada, 35017 Las Palmas de GC, Spain [2]Division of Surgery and Interventional Science, University College London, Stanmore, London HA7 4LP, UK [3]3Bs Biomaterials, Biodegradables and Biomimetics, Universidade Do Minho, Parque de Ciencia e Tecnologia Zona Industrial da Gandra, 4805-17 Barco GMR, Portugal [4]Integrated and Advanced Manufacturing Processes Research Group, Universidad de Las PaJmas de Gran Canaria, Edificio de fabricacion integrada, 35017 Las Palmas de GC, Spain

出　　处：《Bio-Design and Manufacturing》2018年第1期69-75,共7页生物设计与制造（英文）

摘　　要：Introduction Osteoarthritis （OA） is a degenerative joint disease, characterized by cartilage loss and changes in bone at the interface of a joint resulting in pain, stiffness and reduced mobility. OA is one of the most prevalent chronic conditions as identified in Bone and Joint Decade. According to the World Health Organization, 40% of people over the age of 70 have OA. This joint disease affects around 0.4 billion people with patients in Europe accounting for up to 30%. The figure is set to increase with the ageing problem.

关 键 词：骨性关节炎 疾病 治疗方法 生物技术 

分 类 号：Q753[生物学—分子生物学] Q81