某妇产医院临床分离病原菌及其耐药趋势分析  

Trend analysis on pathogen resistance of a gynecology and obstetrics hospital

作　　者：吴思奇 戎惠娟[1] 张敬蕊 赵春超 WU Si-qi;Rong Hui-juan;ZHANG Jing-rui;ZHAO Chun-chao(The Fourth Hospital of Shijiazhuang,Shijiazhuang Hebei 050011,China)

机构地区：[1]石家庄市第四医院,河北石家庄050011

出　　处：《中国消毒学杂志》2018年第10期770-772,共3页Chinese Journal of Disinfection

摘　　要：目的了解妇产专科医院临床分离病原菌分布及其耐药性变化趋势,为临床合理用药提供依据。方法采用病原菌分离鉴定方法,对某妇产医院临床患者送检病原学标本进行检测与分析。结果从该医院连续3年送检的临床标本中共检出病原菌18 985株,其中真菌为主要优势菌群,占分离菌株总数63.59%;其次是革兰阳性菌和革兰阴性菌,分别占23.97%和12.44%。病原菌以白假丝酵母菌居首位,占45.90%;其次是光滑假丝酵母菌和B群链球菌,分别占12.79%和11.57%。B群链球菌对阿奇霉素、克林霉素和红霉素耐药率均接近80.1%;金黄色葡萄球菌对青霉素、红霉素、阿奇霉素和克拉霉素耐药率在96.6%~73.8%;大肠埃希菌对氨苄西林等抗菌药物高度耐药。结论妇产医院临床标本分离病原菌以真菌为主,革兰阳性菌对抗菌药物耐药趋势发展明显。Objective To understand the distribution of clinical pathogenic bacteria and drug resistance of a gynecology and obstetrics hospital,so as to provide basis for clinical rational use of antimicrobial drugs. Methods All the pathogen samples were tested and analyzed through the isolation and identification method of pathogenic bacteria. Results A total of18 985 strains pathogenic bacteria were detected in 3 years,fungi were the main bacteria,accounting for 63. 59% of the total number of isolated strains. Followed by Gram-positive bacteria and Gram-negative bacteria,accounted for 23. 97% and12. 44% respectively. Among the pathogens,Candida albicans ranked first,accounting for 45. 90%,followed by Candida glabrata and Group B streptococci,accounting for 12. 79% and 11. 57%,respectively. Antibiotic resistance rate of group B streptococcus to azithromycin,clindamycin and erythromycin were all close to 80. 1%. Antibiotic resistance rate of Staphylococcus aureus to penicillin,erythromycin,azithromycin and clarithromycin ranged from 96. 6% to 73. 8%. Escherichia coli showed high resistance to ampicillin. Conclusion Fungi is the pathgon in gynecdogy and obstetrics hospital. And Gram-positive bacteria shows high resistance to antimicrobial drugs.

关 键 词：妇产医院 病原菌 耐药性 

分 类 号：R378[医药卫生—病原生物学]