糖平宝的淀粉酶抑制作用  

Inhibition of a Chinese Herb FormulaTangpingbao on Amylase Activity

作　　者：陈红宾[1] 马丽焱[1] 江京俐[1] 於兰[1] 孙立红[1] 郭屹[1] 

机构地区：[1]中国医学科学院药用植物研究所

出　　处：《中国实验方剂学杂志》1995年第1期14-17,共4页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：糖平宝是治疗糖尿病的中药方剂。用昆明种小鼠实验观察糖平宝（ＴＰＢ）的降血糖作用，发现ＴＰＢ对正常小鼠淀粉负荷糖耐量有增强作用；对四氧嘧啶性糖尿病小鼠淀粉负荷后高血糖有降糖作用。但它对正常小鼠的葡萄糖耐量则无影响。表明ＴＰＢ的降血糖作用与其抑制消化道淀粉酶活性有关。A Chinese drug formula Tangpingbao is composed of some Chi-nese herbs and used to treat diabetes. Hypoglycemic aetivity of Tangpingbao wasinvestigated in kunnming mice. Tangpingbao was found to smooth the hyper-glycemia caused by starch一loading at both normal and alloxan一induced di-abetic mice. But it did not decrease hyperglycemia caused by glucose. We came tothe conclusion that Tangpingbao is an amylase inhibitor decreasing intraluminalamylase activity on starch digestion.

关 键 词：抑制作用 糖平宝 淀粉酶 糖尿病 血糖 

分 类 号：R259.871[医药卫生—中西医结合] R285.5[医药卫生—中医内科学]