痛经丸对动物子宫平滑肌的抑制作用  

Inhibitory Effects of Tongjing Pill on Uterine Smooth Muscles in Animals

作　　者：昌兰芳[1] 孙江桥[1] 蔡大勇 何功倍 

机构地区：[1]湖北中医学院中药研究所

出　　处：《中国实验方剂学杂志》1995年第1期25-28,共4页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：痛经丸对家兔在位子宫、子宫瘘子宫、大鼠和豚鼠离体子宫有明显的抑制作用，表现在子宫的收缩频率减慢，收缩振幅变低，子宫肌张力下降。它还能对抗ＰＧＦ２。所致小鼠离体子宫肌痉挛。这可能是它治疗痛经的机理之一。Tongjing pill is a Chinese traditional patent medicine.Significant inhi bitory action of Tongjing pill was observed on isolated uterus in rats and guinea pigs, and on uterus in situ or uterus with fistula in rabbits. The inhibition of Tongiing pill on uterus was characterized by lowering contraction frequency and amplitude, and tension of uterine smooth muscles. Tongjing pill could also antagonize FGI2a一induced spaxm in the isolated uterus from the mouse. These inhibitory effects of Tongiing bill may be correlated to mechanism of its treating primary dysmenorrhea.

关 键 词：子宫平滑肌 抑制作用 痛经丸 痛经 肌痉挛 

分 类 号：R271.113[医药卫生—中医妇科学] R285.5[医药卫生—中医学]