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作 者:宋玙璠 谈秀娟 马雯雯[1] 刘艳娟[1] 宋坤琨 张明敏[1] Song Yufan;Tan Xiujuan;Ma Wenwen;Liu Yanjuan;Song Kunkun;Zhang Mingmin(Tongji Hospital,Tong]i Medical College,Huazhong University of Science.and Technology,Wuhan 430030,China)
机构地区:[1]华中科技大学同济医学院附属同济医院,武汉430030
出 处:《中华生殖与避孕杂志》2018年第9期774-778,共5页Chinese Journal of Reproduction and Contraception
摘 要:系统性红斑狼疮(SLE)是一种威胁育龄期女性生殖健康的慢性、多系统的自身免疫性疾病,其对母体、胎儿的不良影响给临床医生提出了巨大挑战。有效的孕前风险评估、合理的孕期监测及各个时期的合理用药对于SLE患者母、胎健康至关重要。本文讨论了SLE与妊娠之间的相互影响、妊娠期风险评估和病情监测,归纳了抗风湿药物的围妊娠期使用安全性,以便于临床上更好地指导SLE患者的妊娠。Systemic lupus erythematosus(SLE) is a chronic and multi-systemic autoimmune disease, which most commonly strikes women in their childbearing age and puts forward a tremendous challenge to clinicians concerning its negative effect to mother and fetus. Effective risk evaluation, appropriate pregnancy monitoring and medical treatment are of crucial importance for the health of SLE mother and fetus. Through our review, we conclude the interaction between SLE and pregnancy, risk evaluation and disease monitoring of SLE, as well as the security of anti-rheumatic drugs around the time of pregnancy so as to clinically guide SLE women to get pregnancy successfully.
关 键 词:系统性红斑狼疮(SLE) 妊娠 风险评估 妊娠并发症 药物治疗
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