目标导向液体治疗对异位妊娠失血性休克患者组织灌注的影响  

Effects of target - oriented fluid therapy on the tissue perfusion of patients with hemorrhagic shock during ectopic pregnancy

作　　者：孙玉川[1] 王殿涛[1] Sun Yuchuan;Wang Diantao(Department of Anesthesiology,Laiyang Central Hospital of Yantai,Laiyang,Shandong 265131,China)

机构地区：[1]烟台市莱阳中心医院麻醉科,山东省莱阳265131

出　　处：《中国基层医药》2018年第18期2391-2393,共3页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的 探讨目标导向液体治疗对异位妊娠失血性休克患者组织灌注的影响.方法 选择2015年12月至2017年6月烟台市莱阳中心医院收治的异位妊娠失血性休克患者80例为研究对象,采用随机数字表法分为两组各40例,对照组予常规液体补充,观察组予目标导向液体治疗.比较两组平均动脉压、中心静脉压及尿量,统计两组血管活性药物使用率及使用时间.结果 观察组平均动脉压为（115.6±10.3）mmHg,高于对照组的（86.9±5.6）mmHg（t=15.482,P〈0.05）;中心静脉压为（7.1±0.5）cmH2O,高于对照组的（5.9±0.2）cmH2O（t=14.093,P〈0.05）;尿量为（256.8±15.9）mL,多于对照组的（53.1±5.0）mL（t=77.294,P〈0.05）;观察组血管活性药物使用率为7.5％,低于对照组的37.5％（t=8.674,P〈0.05）;血管活性药物使用时间为（35.0±0.1）min,短于对照组的（49.6±1.8）min（t=13.707,P〈0.05）.结论 针对异位妊娠失血性休克患者行目标导向液体治疗,能更有效的进行液体复苏,减少血管活性药物使用.Objective To investigate the effect of target -oriented fluid therapy on the tissue perfusion of patients with hemorrhagic shock during ectopic pregnancy .Methods From December 2015 to June 2017 ,80 patients with ectopic pregnancy hemorrhagic shock in Laiyang Central Hospital of Yantai were enrolled in this study .They were divided into two groups according to the random number method ,with 40 cases in each group .The control group was given routine fluid supplementation .The observation group was given target -oriented fluid therapy .The average arterial pressure,central venous pressure and urine output in two groups were compared .The vasoactive drug use and use time were analyzed in the two groups .Results The mean arterial pressure in the observation group was （115.6 ±10.3）mmHg,which was higher than that in the control group [（86.9 ±5.6）mmHg]（t=15.482,P〈0.05）.The central venous pressure in the observation group was （7.1 ±0.5）cmH2O,which was higher than that in the control group [（5.9 ±0.2）cmH2O]（t =14.093,P〈0.05）.The urine output in the observation group was （256.8 ±15.9）mL,which was more than （53.1 ±5.0）mL in the control group（t=77.294,P〈0.05）.The use rate of vasoactive drug in the observation group was 7.5%,which was lower than 37.5%in the control group（t=8.674, P〈0.05）.The duration of vasoactive drug use in the observation group was （35.0 ±0.1）min,which was shorter than （49.6 ±1.8）min in the control group（t=13.707,P〈0.05）.Conclusion Target-oriented fluid therapy for ectopic pregnancy hemorrhagic patients is more effective for fluid resuscitation and less usage of vasoactive drugs .

关 键 词：妊娠 异位 休克 出血性 液体复苏 中心静脉压 

分 类 号：R714.22[医药卫生—妇产科学]