髋部骨折患者的肌少症相关危险因素分析  

Analysis on related risk factors of hip fracture patient with sarcopenia

作　　者：郎俊哲[1] 章轶鸥 金建锋 吴鹏[1] 陈雷[1] LANG Jun-zhe;ZHANG Yi-ou;JIN Jian-feng;WU Peng;CHEN Lei(Department of Othopaedics,the First Affiliated Hospital of Wenzhou Medical University,Wenzhou 325000,Zhejiang,China)

机构地区：[1]温州医科大学附属第一医院骨科,浙江温州325000

出　　处：《中国骨伤》2018年第10期912-915,共4页China Journal of Orthopaedics and Traumatology

摘　　要：目的:探讨肌少症在髋部骨折患者中的发生率及相关风险因素。方法:自2013年5月至2017年1月收治髋部骨折患者187例,男99例,女88例;年龄50～95(77.40±10.58)岁。观察分析患者的一般情况、四肢骨骼肌质量指数(ASMI)、脂肪总量、骨矿含量(BMC)、身体质量指数(BMI),握力、术前血维生素D、血白蛋白、美国麻醉医师协会分级评分(ASA)及NMS运动评分。根据握力和ASMI,将患者并分为肌少症组与非肌少症组,采用单因素及多因素分析统计分析。结果:符合肌少症诊断的患者99例(52.9%),与非肌少症组相比,肌少症的发生与高龄、高ASA、低脂肪总量、低骨矿含量、低BMI,低白蛋白、低NMS评分相关,随后进行的二元Logistic回归分析提示高龄(OR=1.804,P=0.048),高ASA评分(OR=3.052,P=0.001),低脂肪总量(OR=0.843,P=0.006),低骨矿含量(OR=0.203,P=0.026)是髋部骨折患者肌少症发生的相关因素。结论:高龄、高ASA评分、低脂肪总量。Objective：To explore occurrence and risk factors of sarcopenia in patients with hip facture. Methods：From May 2013 to January 2017,187 patients with hip fractures were collected,including 99 males and 88 females aged from 50 to 95 years old with an average age of（77.40±10.58） years old. General conditions,appendicular skeletal muscle index（ASMI）,total fat mass,bone mineral content（BMC）,body mass index（BMI）,grip strength,preoperative blood vitamin D（VITD）,albumin,American Society of Anesthesiologists（ASA） classification and new mobility scores（NMS） were observed and analyzed.According to grip strength and ASMI,patients were divided into sarcopina group and non sarcopina group,univariate and multivariate statistical methods were used to analyzed. Results：Ninty nine patients（52.9%） were diagnosed as sarcopenia. Compared with non-sarcopenia group,occurrence of sarcopenia was associated with advanced age,high ASA,low total fat mass,low bone mineral content,low BMI,low albumin,and low NMS. Subsequent binary logistic regression analysis showed that advanced age（OR =1.804,P =0.048）,high ASA score（OR =3.052,P =0.001）,low fat content（OR =0.843,P =0.006）,low bone mineral salt（OR=0.203,P =0.026） were risk factors of hip fracture patient with sarcopenia. Conclusion：Old age,high ASA score,low fat content,low bone mineral content may be related risk factors for sarcopenia in hip fracture patients.

关 键 词：髋 骨折 危险因素 

分 类 号：R683[医药卫生—骨科学] R685[医药卫生—外科学]